Researcher
Tom Vanden Berghe
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 5 of 5
- Investigating the immunoregulatory properties of ferroptosis in experimental cancer modelsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- Therapeutic exploration of lead ferroptosis inhibitors in multiple sclerosis - grant 2020From1 Jan 2020 → 30 Jun 2021Funding: Foundations, funds and other with scientific goal
- Therapeutic exploration of lead ferroptosis inhibitors in multiple sclerosisFrom1 Jan 2019 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Nanoparticle-based ferroptosis-induction tot treat neuro-and glioblastomaFrom1 Jan 2019 → 31 Dec 2021Funding: Foundations, funds and other with scientific goal
- Study of the in vivo role of effector caspases (patho-) physiological model systems.From1 Oct 2007 → 30 Sep 2013Funding: BOF - Other initiatives, FWO fellowships
Publications
1 - 10 of 104
- Ferroptosis and pyroptosis signatures in critical COVID-19 patients(2023)
Authors: Cédric Peleman, Samya Van Coillie, Symen Ligthart, Jan De Waele, Pieter Depuydt, Dominique Benoit, Hannah Schaubroeck, Sven M. Francque, Karolien Dams, Rita Jacobs, et al.
Pages: 2066 - 2077 - Caspase inhibition modulates monocyte-derived macrophage polarization in damaged tissues(2023)
Authors: Stéphanie Solier, Michele Mondini, Lydia Meziani, Arnaud Jacquel, Catherine Lacout, Tom Vanden Berghe, Yvon Julé, Jean-Claude Martinou, Gérard Pierron, Julie Rivière, et al.
- Apoptotic cell death in disease : current understanding of the NCCD 2023(2023)
Authors: Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A Aaronson, John M Abrams, Dieter Adam, Massimiliano Agostini, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, et al.
Pages: 1097 - 1154 - Beyond ferrostatin-1 : a comprehensive review of ferroptosis inhibitors(2023)
Authors: Camilla Scarpellini, Greta Klejborowska, Caroline Lanthier, Behrouz Hassannia, Tom Vanden Berghe, Koen Augustyns
Pages: 902 - 916 - Molecular mechanisms of nemorosone-induced ferroptosis in cancer cells(2023)
Authors: Roberto Fernández-Acosta, Jurgen Caroen, Bartosz Wiernicki, Daniel Alvarez-Alminaque, Johan Van der Eycken, Peter Vandenabeele, Tom Vanden Berghe, Gilberto L. Pardo-Andreu
- RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD(2023)
Authors: Hannelore Van Eeckhoutte, Chantal Donovan, Richard Y. Kim, Thomas M. Conlon, Meshal Ansari, Haroon Khan, Ranjith Jayaraman, Nicole G. Hansbro, Yves Dondelinger, Tom Delanghe, et al.
- Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression(2023)
Authors: Emily Van San, Angela Debruyne, Geraldine Veeckmans, Yulia Y. Y. Tyurina, Vladimir A. A. Tyurin, Hao Zheng, Sze Men Choi, Koen Augustyns, Geert van Loo, Bernhard Michalke, et al.
Pages: 2092 - 2103 - Targeting ferroptosis protects against experimental (multi)organ dysfunction and death(2022)
Authors: Samya Van Coillie, Emily Van San, Ines Goetschalckx, Bartosz Wiernicki, Banibrata Mukhopadhyay, Wulf Tonnus, Ria Roelandt, Catalina Dumitrascu, Ludwig Lamberts, Geert Dams, et al.
- Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state(2022)
Authors: Farzaneh Ghazavi, Jelle Huysentruyt, Stephanie Kourula, Sofie Martens, Tim Wartewig, Tatyana Divert, Ria Roelandt, Bastian Popper, Andreas Hiergeist, Peter Tougaard, et al.
- Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity(2022)
Authors: Bartosz Wiernicki, Sophia Maschalidi, Jonathan Pinney, Sandy Adjemian Catani, Tom Vanden Berghe, Kodi Ravichandran, Peter Vandenabeele
Patents
1 - 6 of 6
- COMPOUNDS FOR INHIBITING CELL DEATH (Inventor)
- COMPOUNDS FOR INHIBITING CELL DEATH (Inventor)
- 3,4-diaminobenzenesulfonamide derivatives for inhibiting cell death (Inventor)
- COMPOUNDS FOR INHIBITING CELL DEATH (Inventor)
- Targeting of Interleukin-1 and -18 in treatment of septic shock (Inventor)
- 3,4-diaminobenzenesulfonamide derivatives for inhibiting cell death (Inventor)