Researcher
Peter de Witte
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Molecular Biodiscovery (Division)
Responsible
From1 Apr 2013 → Today - Molecular Biodiscovery (Division)
Member
From1 Apr 2013 → Today
Projects
1 - 10 of 31
- PHGDH-ASM: Phosphoglycerate dehydrogenase (PHGDH) activators as novel antiseizure medications (ASM) with dual mode of actionFrom1 Oct 2022 → TodayFunding: IOF - technology validation in lab
- Excitation-inhibition imbalance in autism-epilepsy comorbidity, a preclinical and clinical studyFrom1 Oct 2021 → 30 Sep 2023Funding: BOF - projects
- Development of innovative multi-dimensional liquid chromatography methods for the analysis of organic micropollutants and their degradation products in environmental waterFrom1 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Therapeutic strategies for Dravet syndrome: upregulation of endogenous SCN1A and modulation of remodelingFrom1 Jun 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Multi-dimensional liquid chromatography for the analysis of complex samples.From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- SmartDetox - Removal of organic micropollutants from waterFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Unraveling the in vivo host cell tropism and virus dissemination strategies of human norovirus.From28 Sep 2020 → TodayFunding: FWO fellowships
- A Lattice Light Sheet microscope to image subcellular molecular dynamics, cellular forces, neuroimmune interactions and neuronal activity in 3DFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Toxicity assessment of degradation products using zebrafish and advanced LC-MS techniquesFrom6 Jan 2020 → 6 Jan 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- An antisense strategy and network pharmacology approach in zebrafish models to identify novel targets for pharmacoresistant epilepsyFrom1 Nov 2019 → 30 Sep 2023Funding: FWO Strategic Basic Research Grant
Publications
111 - 120 of 146
- Evans blue as a selective dye marker for white-light diagnosis of non-muscle-invasive bladder cancer: an in vitro study(2012)
Authors: Ben Van Cleynenbreugel, Evelyne Lerut, Hendrik Van Poppel, Peter de Witte
Pages: 300 - 5 - Influence of the vascular damaging agents DMXAA and ZD6126 on hypericin distribution and accumulation in RIF-1 tumors(2011)
Authors: Evelyne Lerut, Peter de Witte
Pages: 1619 - 1627 - Assessment of the convulsant liability of antidepressants using zebrafish and mouse seizure models(2011)
Authors: Tatiana Afrikanova, Alex Crawford, Camila Esguerra, Peter de Witte
Pages: 450 - 460 - A Dual-targeting Anticancer Approach: Soil and Seed Principle(2011)
Authors: Junjie Li, Marlein Miranda Cona, Feng Chen, Lin Zhou, Johan Nuyts, Guy Bormans, Peter de Witte, Alfons Verbruggen, Luc Mortelmans, Guy Marchal, et al.
Pages: 799 - 807 - Radiolabeled Iodohypericin as Tumour Necrosis Avid Tracer - Diagnostic and Therapeutic Potential(2011)
Authors: Guy Bormans, Alfons Verbruggen, Peter de Witte
Pages: S153 - S154 - Use of fluorescein isothiocyanate-human serum albumin for the intravesical photodiagnosis of non-muscle-invasive bladder cancer: an in vitro study using multicellular spheroids composed of normal human urothelial and urothelial cell carcinoma cell lines(2011)
Authors: Ben Van Cleynenbreugel, Hendrik Van Poppel, Evelyne Lerut, Peter de Witte
Pages: 455 - 459 - Purification of Nano-Porous Silicon for Biomedical Applications(2011)
Authors: Peter de Witte
Pages: B225 - B233 - Biodistribution of PVP-hypericin and hexaminolevulinate-induced PpIX in normal and orthotopic tumor-bearing rat urinary bladder(2011)
Authors: Ben Van Cleynenbreugel, Hendrik Van Poppel, Peter de Witte
Pages: 775 - 781 - Photodynamic therapy using topically applied hypericin: Comparative effect with methyl-aminolevulinic acid on UV induced skin tumours(2011)
Authors: Rik Roelandts, Peter de Witte
Pages: 123 - 131 - Zebrafish bioassay-guided natural product discovery: Isolation of angiogenesis inhibitors from East African medicinal plant(2011)
Authors: Alex Crawford, Sandra Liekens, Sebastian Munck, Roger Busson, Jef Rozenski, Camila Esguerra, Peter de Witte
Patents
1 - 10 of 10
- Treatment of pharmacoresistant epilepsy (Inventor)
- Idebenone in the treatment of drug resistant epilepsy (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Anticonvulsant activity of bisabolene sesquiterpenoids isolated from turmeric oil (Inventor)
- Anticonvulsant activity of turmeric oil and bisabolene sesquiterpenoids (Inventor)