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Researcher
Peter de Witte
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Molecular Biodiscovery (Division)
Responsible
From1 Apr 2013 → Today - Molecular Biodiscovery (Division)
Member
From1 Apr 2013 → Today
Projects
21 - 30 of 31
- In vivo modeling of epileptic encephalopathies caused by mutations in aminoacyl-tRNA synthetases in zebrafish.From1 Oct 2015 → 30 Sep 2018Funding: FWO fellowships
- Zebrafish as a novel organism model to study immunogenic cell death-related mechanismsFrom1 Oct 2015 → 1 Aug 2017Funding: FWO fellowships
- New treatment of cystinosis.From1 Mar 2015 → 28 Feb 2020Funding: FWO research project (including WEAVE projects)
- Pathophysiology of epileptic encephalopathies: insights from genetics in patients and in vivo modelling in zebrafish and fruit flies.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project
- Zebrafish - a small-animal model for ADME studiesFrom1 Jan 2014 → 19 Dec 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Zebrafish-based discovery of antiseizure natural products: focus on secondary metabolites from marine microorganismsFrom17 Sep 2012 → 28 Aug 2017Funding: BOF - Doctoral projects
- Evans blue as a diagnostic tool for non-muscle-invasive bladder cancer and interstitial cystitis : a preclinical study.From1 Oct 2011 → 30 Sep 2016Funding: BOF - Concerted Research Project from 1994
- Establishment of zebrafish model of attention-deficit/hyperactivity disorderFrom1 Dec 2010 → 15 Jul 2016Funding: IWT personal funding - strategic basic research grants
- Functional analysis of novel, small-molecule modulators of BMP and Wnt signaling in zebrafish.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Functional Peptidomics Knowledge Platform.From1 Oct 2009 → 30 Sep 2013Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 146
- Detailed comparison of in-house developed and commercially available heart-cutting and selective comprehensive two-dimensional liquid chromatography systems(2024)
Authors: Peter de Witte, Deirdre Cabooter
- New Phocoenamicin and Maklamicin Analogues from Cultures of Three Marine-Derived Micromonospora Strains(2023)
Authors: Peter de Witte
- Electrochemical degradation of 17α-ethinylestradiol: Transformation products, degradation pathways and in vivo assessment of estrogenic activity(2023)
Authors: Peter de Witte, Deirdre Cabooter
- Optimizing transfer and dilution processes when using active solvent modulation in on-line two-dimensional liquid chromatography(2023)
Authors: Soraya Chapel, Peter de Witte, Deirdre Cabooter
- The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae(2022)
Authors: Arno Cuvry, Dufie Strubbe, Johan Neyts, Peter de Witte, Joana Duarte Da Rocha Pereira
- Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor(2022)
Authors: Aleksandra Siekierska, Peter de Witte, Daniëlle Copmans
- Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities(2022)
Authors: Ann-Sofie De Meulemeester, Lise Heylen, Aleksandra Siekierska, Peter de Witte
- Modeling mTORopathies in zebrafish(2022)
Authors: Ann-Sofie De Meulemeester, Peter de Witte, Lieven Lagae
- Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction(2022)
Authors: Isabelle Adant, Bram Decru, Peter de Witte, Daisy Rymen, Peter Witters, Pieter Vermeersch, David Cassiman, Bart Ghesquière
- Development of compounds for the treatment of drug-resistant epilepsies(2022)
Authors: Gert Steurs, Wim De Borggraeve, Peter de Witte
Patents
1 - 10 of 10
- Treatment of pharmacoresistant epilepsy (Inventor)
- Idebenone in the treatment of drug resistant epilepsy (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Anticonvulsant activity of bisabolene sesquiterpenoids isolated from turmeric oil (Inventor)
- Anticonvulsant activity of turmeric oil and bisabolene sesquiterpenoids (Inventor)