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Researcher
Ludo Van Den Bosch
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Responsible
From1 Oct 2018 → Today - Van Den Bosch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2012 → Today - Research Group Experimental Neurology (Division)
Member
From1 Oct 2002 → 31 Dec 2011
Projects
21 - 30 of 60
- Determining the role of KIF5A in amyotrophic lateral sclerosis (ALS) pathogenesisFrom1 Oct 2019 → 30 Sep 2023Funding: FWO fellowships
- Investigating mitochondrial transport in sporadic ALSFrom6 Sep 2019 → 6 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Contribution of osmotic stress and long non codings RNAs to drug tolerance in melanomaFrom28 Jan 2019 → 28 Jan 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Unravelling genetic modifiers of Amyotrophic Lateral Sclerosis (ALS) caused by mutations in FUS and TDP-43From16 Jan 2019 → TodayFunding: FWO fellowships
- Identification, characterization and validation of modifiers of repeat RNA toxicity in C9orf72 amyotrophic lateral sclerosis (ALS)From1 Oct 2018 → 28 Feb 2023Funding: FWO fellowships
- Modeling Amyotrophic Lateral Sclerosis: Human iPSC-derived Astrocytes and Neuromuscular Junctions in Microfluidic DevicesFrom15 May 2018 → 18 Nov 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of stress granules in amyotrophic lateral sclerosis (ALS)From1 Jan 2018 → 1 Jan 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of axonal transport in amyotrophic lateral sclerosis (ALS) using motor neurons differentiated from induced pluripotent stem cells (iPSCs)From1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- TDP-43 aggregates in Amyotrophic Lateral Sclerosis (ALS): composition and biological effectsFrom1 Nov 2017 → 31 Dec 2022Funding: FWO Strategic Basic Research Grant
- Chemical tools for investigating epigenetic modulation and calcium mediated synaptic plasticityFrom23 Oct 2017 → 9 Dec 2022Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 231
- FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.(2024)
Authors: Ludo Van Den Bosch
Pages: 2156 - The sense of antisense therapies in ALS.(2024)
Authors: Philip Van Damme, Ludo Van Den Bosch
Pages: 252 - 262 - TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish(2024)
Authors: Philip Van Damme, Dietmar Thal, Valérie Bercier, Ludo Van Den Bosch
- Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies.(2024)
Authors: Ludo Van Den Bosch
Pages: e4936 - PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport.(2024)
Authors: Thibaut Burg, Philip Van Damme, Ludo Van Den Bosch
Pages: 41 - Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit(2023)
Authors: Ludo Van Den Bosch
Pages: 1821 - 1843 - Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Basiel Cole, Maxime Vanmechelen, Bram Boeckx, Diether Lambrechts, Ludo Van Den Bosch, Steven De Vleeschouwer, Frederik De Smet
- Proteostasis plays an important role in demyelinating Charcot Marie Tooth disease.(2023)
Authors: Ludo Van Den Bosch
Pages: 115760 - lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons(2023)
Authors: Ludo Van Den Bosch
- TDP‑43 pathology is associated with increased tau burdens and seeding(2023)
Authors: Sandra Oliveira Tomé, Grigoria Tsaka, Klara Gawor, Philip Van Damme, Ludo Van Den Bosch, Rik Vandenberghe, Frederic Rousseau, Joost Schymkowitz, Dietmar Thal
Patents
1 - 4 of 4