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Researcher
Ludo Van Den Bosch
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Responsible
From1 Oct 2018 → Today - Van Den Bosch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Neurobiology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2012 → Today - Research Group Experimental Neurology (Division)
Member
From1 Oct 2002 → 31 Dec 2011
Projects
41 - 50 of 60
- Investigating modifiers of C9orf72 induced pathology in Amyotrophic Lateral Sclerosis (ALS) using zebrafish.From1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships
- Unraveling the role of the hypoxia factor HIF-2a in muscle atrophy.From1 Oct 2014 → 31 Dec 2019Funding: BOF - Doctoral projects, FWO Strategic Basic Research Grant
- Modulation and recording of circuit activity using double opticsFrom10 Sep 2014 → 9 Mar 2019Funding: Hercules - Small and Medium size research infrastructure
- The mechanism of mutant C9orf72 in the pathogenesis of Amyotrophic Lateral Sclerosis/Frontotemporal Lobe Degeneration.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- The role of long non-coding RNAs in spinal muscular atrophy.From1 Oct 2013 → 30 Sep 2016Funding: FWO fellowships
- Biological effects of progranulin in axonal regeneration and FTDFrom1 Sep 2013 → 9 Oct 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of the pathogenic mechanism and identification of disease-modifying genes in FUS-induced amyotrophic lateral sclerosis (ALS).From1 Sep 2013 → 31 Dec 2017Funding: IWT personal funding - strategic basic research grants
- Local protein synthesis and degradation in neuromuscular disorders.From1 Oct 2012 → 30 Sep 2013Funding: BOF - Other initiatives
- The role of histon deacetylase 6 (HDAC6) in peripheral axonal neuropathies and amyotrophic lateral sclerosis (ALS).From1 Sep 2012 → 28 Mar 2018Funding: IWT personal funding - strategic basic research grants
- Wordkstation for high speed and resolution imaging of living animals by confocal multiphoton laser scanning microscopy.From28 Jun 2012 → 27 Dec 2018Funding: Hercules - Small and Medium size research infrastructure
Publications
1 - 10 of 231
- FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.(2024)
Authors: Ludo Van Den Bosch
Pages: 2156 - The sense of antisense therapies in ALS.(2024)
Authors: Philip Van Damme, Ludo Van Den Bosch
Pages: 252 - 262 - TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish(2024)
Authors: Philip Van Damme, Dietmar Thal, Valérie Bercier, Ludo Van Den Bosch
- Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies.(2024)
Authors: Ludo Van Den Bosch
Pages: e4936 - PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport.(2024)
Authors: Thibaut Burg, Philip Van Damme, Ludo Van Den Bosch
Pages: 41 - Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit(2023)
Authors: Ludo Van Den Bosch
Pages: 1821 - 1843 - Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma(2023)
Authors: Lise Finotto, Basiel Cole, Maxime Vanmechelen, Bram Boeckx, Diether Lambrechts, Ludo Van Den Bosch, Steven De Vleeschouwer, Frederik De Smet
- Proteostasis plays an important role in demyelinating Charcot Marie Tooth disease.(2023)
Authors: Ludo Van Den Bosch
Pages: 115760 - lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons(2023)
Authors: Ludo Van Den Bosch
- TDP‑43 pathology is associated with increased tau burdens and seeding(2023)
Authors: Sandra Oliveira Tomé, Grigoria Tsaka, Klara Gawor, Philip Van Damme, Ludo Van Den Bosch, Rik Vandenberghe, Frederic Rousseau, Joost Schymkowitz, Dietmar Thal
Patents
1 - 4 of 4