Researcher
Karel Allegaert
- Disciplines:Paediatrics, Pharmacology not elsewhere classified, Neonatology
Affiliations
- Clinical Pharmacology and Pharmacotherapy (Division)
Member
From1 Oct 2019 → 30 Sep 2022 - Woman and Child (Division)
Member
From1 Apr 2013 → 30 Sep 2022
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 22
- Handling of social determinants in pharmacokinetics-pharmacodynamics analyses to enhance equity and inclusion in drug dosing in neonates, children, and adolescentsFrom4 Jan 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Using ‘real-world’ data to gain knowledge on medication safety during pregnancy: towards a ‘fit-for-purpose’ registration system on maternal medication use and mother-infant outcomes (BELpREG).From1 Oct 2023 → TodayFunding: BOF - postdoctoral mandates
- Antibacterial dose optimisation based on augmented renal clearance in adult critically ill patients and selected pediatric patientsFrom1 Oct 2021 → 30 Sep 2022Funding: BOF - postdoctoral mandates
- Exploration of the pharmacokinetics of clindamycin and its metabolites in special patients: from bioanalysis to clinical relevanceFrom1 Oct 2021 → 30 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Drug exposure through lactation: providing neonatal physiology to improve pharmacokinetic predictionsFrom21 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- External and Internal Drivers of Unhealthy AgeingFrom8 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Beyond optimising drug exposure: Pharmacodynamic models to bridge the gap between exposure and response to antimicrobial treatmentsFrom15 Jul 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The development and validation of a prototype of a Belgian data registration system on medication use during pregnancy and lactation (BELpREG-project)From1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- In vitro and in silico investigation of pharmacokinetics in neonates undergoing therapeutic hypothermiaFrom26 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- I-PREDICT: Innovative Physiology-based pharmacokinetic model to pREdict Drug exposure In neonates undergoing Cooling TherapyFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 743
- Modulation of engineered nano/micro material interactions with biological barriers for enhanced or hindered transport(2023)
Authors: Vincent Lenders, Xanthippi Koutsoumpou, Stefaan Soenen, Karel Allegaert, Steven De Vleeschouwer, Jaan Toelen, Bella Manshian
Pages: 4672 - 4724 - Neonatal Pharmacology(2023)
Authors: Karel Allegaert
Pages: 253 - 265Number of pages: 12 - Perfused boundary region as biomarker for endothelial integrity in former preterms in adolescence(2023)
Authors: Liselotte Van Loo, Karel Allegaert, Elena Levtchenko, Zhenyu Zhang, Jan A Staessen
Pages: 1936 - 1942 - Infant exposure to Fluvoxamine through placenta and human milk: a case series-A contribution from the ConcePTION project(2023)
Authors: Karel Allegaert
- Development and design of the BELpREG registration system for the collection of real-world data on medication use in pregnancy and mother-infant outcomes(2023)
Authors: Laure Sillis, Veerle Foulon, Karel Allegaert, Annick Bogaerts, Maarten De Vos, Anne Smits, Kristel Van Calsteren, Jan Verbakel, Michael Ceulemans
- Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling—A Contribution from the ConcePTION Project(2023)
Authors: Nina Nauwelaerts, Miao-Chan Huang, Martje Van Neste, Anne Smits, Karel Allegaert, Pieter Annaert
- Neonatal Drug Formularies-A Global Scope(2023)
Authors: Anne Smits, Karel Allegaert
- Safety of medicines during breastfeeding - from case report to modeling: a contribution from the ConcePTION project(2023)
Authors: Nina Nauwelaerts, Karel Allegaert, Anne Smits, Pieter Annaert
Pages: 269 - 283 - Development of a neonatal Gottingen Minipig model for dose precision in perinatal asphyxia: technical opportunities, challenges, and potential further steps(2023)
Authors: Karen Leys, Pieter Annaert, Sebastien Carpentier, Anne Smits, Karel Allegaert
- Pre- and postnatal medical therapies for congenital diaphragmatic hernia-related pulmonary hypertension.(2023)
Authors: Felix De Bie, Jan Deprest, Karel Allegaert, Francesca Maria Russo