Researcher
Frederic Rousseau
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
- See also: Frederic Rousseau (Flanders Institute for Biotechnology)
Affiliations
- Switch Laboratory (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Projects
1 - 10 of 51
- New molecular tools for diagnostic and treatment of systemic amyloidosisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Structural and morphological studies of heterotypic amyloid fibrilsFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Cotranslational protein folding and aggregationFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of Heterotypic Interactions of TDP-43 Aggregation in NeurodegenerationFrom11 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2022 → 30 Sep 2023Funding: BOF - postdoctoral mandates
- Structural dynamics basis of function in the SecB chaperoneFrom19 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Heterotypic amyloid interactions as modulators of selective cellular vulnerabilityFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
Publications
101 - 110 of 156
- Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics(2017)
Authors: Steven Boeynaems, Elke Bogaert, Mathias De Decker, Thomas Vercruysse, Dirk Daelemans, Joost Schymkowitz, Frederic Rousseau, Wim Robberecht, Philip Van Damme, Ludo Van Den Bosch
Pages: 1044 - 1055 - De novo design of a biologically active amyloid(2016)
Authors: Rodrigo Gallardo, Frederik De Smet, Filip Claes, Laleh Khodaparast, Ladan Khodaparast, Tobias Langenberg, Maxime Siemons, Manoj Kumar Gautam, Manu Beerens, Aernout Luttun, et al.
- Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling (vol 23, pg 489, 2013)(2016)
Authors: Corentin Herbert, Ulrich Schieborr, Krishna Saxena, Jarek Juraszek, Frederik De Smet, Chantal Alcouffe, Marc Bianciotto, Giorgio Saladino, David Sibrac, Denis Kudlinzki, et al.
Pages: 176 - 178 - Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling(2016)
Authors: Rodrigo Gallardo, Rudra Shankar Kashyap, Joost Schymkowitz, Frederic Rousseau, Pascale Zimmermann
- Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool(2016)
Authors: Arunkumar Tharkeshwar Raghunath, Roger Habets, Rosanne Wouters, Sebastian Munck, Rita Derua, Etienne Waelkens, Mathieu Bollen, Joost Schymkowitz, Frederic Rousseau, Bart De Strooper, et al.
Pages: 193 - 208 - Sequence-specific protein aggregation generates defined protein knockdowns in plants(2016)
Authors: Rodrigo Gallardo, Frederik De Smet, Frederic Rousseau, Joost Schymkowitz
Pages: 773 - 787 - Protein aggregation as an antibiotic design strategy(2016)
Authors: Johan Van Eldere, Rodrigo Gallardo, Joost Schymkowitz, Frederic Rousseau
Pages: 849 - 65 - Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD(2016)
Authors: Steven Boeynaems, Elke Bogaert, Emiel Michiels, Jolien Steyaert, Kevin Verstrepen, Patrick Callaerts, Frederic Rousseau, Joost Schymkowitz, Philip Van Damme, Wim Robberecht, et al.
- Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis(2016)
Authors: Natalie De Geest, Rob van der Kant, Joost Schymkowitz, Frederic Rousseau, Mathieu Bollen, Monique Beullens, Pierre Vanderhaeghen, Bassem Hassan
Pages: 460 - 475 - From Binding-Induced Dynamic Effects in SH3 Structures to Evolutionary Conserved Sectors(2016)
Authors: Joost Schymkowitz, Frederic Rousseau
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)