Researcher
Frederic Rousseau
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
- See also: Frederic Rousseau (Flanders Institute for Biotechnology)
Affiliations
- Switch Laboratory (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Projects
1 - 10 of 51
- New molecular tools for diagnostic and treatment of systemic amyloidosisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Structural and morphological studies of heterotypic amyloid fibrilsFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Cotranslational protein folding and aggregationFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of Heterotypic Interactions of TDP-43 Aggregation in NeurodegenerationFrom11 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2022 → 30 Sep 2023Funding: BOF - postdoctoral mandates
- Structural dynamics basis of function in the SecB chaperoneFrom19 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Heterotypic amyloid interactions as modulators of selective cellular vulnerabilityFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
Publications
121 - 130 of 156
- Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody(2015)
Authors: Rodrigo Gallardo, Joost Schymkowitz, Frederic Rousseau
Pages: 3700 - 11 - Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody(2015)
Authors: Ki Joon Cho, Bert Schepens, Jong Hyeon Seok, Sella Kim, Kenny Roose, Ji-Hye Lee, Rodrigo Gallardo, Evelien Van Hamme, Joost Schymkowitz, Frederic Rousseau, et al.
Pages: 3700 - 11 - Sequence-dependent internalisation of aggregating peptides(2015)
Authors: Rodrigo Gallardo, Frederik De Smet, Greet De Baets, Wim Annaert, Joost Schymkowitz, Frederic Rousseau
Pages: 242 - 58 - What makes a protein sequence a prion?(2015)
Authors: Frederic Rousseau, Joost Schymkowitz
- Selectivity of aggregation-determining interactions(2015)
Authors: Joost Van Durme, Greet De Baets, Pascale Zimmermann, Johan Van Eldere, Joost Schymkowitz, Frederic Rousseau
Pages: 236 - 47 - Amyloids or Prions? That is the Question(2015)
Authors: Frederic Rousseau, Joost Schymkowitz
Pages: 200 - 6 - The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation(2014)
Authors: Rodrigo Gallardo, Andreea -Alexandra Ungureanu, Virginia Castillo Cano, Carmen Bartic, Frederic Rousseau, Joost Schymkowitz, Bart De Strooper
Pages: 30977 - 89 - A genome-wide sequence-structure analysis suggests aggregation gatekeepers constitute an evolutionary constrained functional class(2014)
Authors: Greet De Baets, Joost Van Durme, Frederic Rousseau, Joost Schymkowitz
Pages: 2405 - 2412 - Horizontal gene transfer from human host to HIV-1 reverse transcriptase confers drug resistance and partly compensates for replication deficits(2014)
Authors: Sarah Megens, Greet De Baets, Guangdi Li, Joost Schymkowitz, Frederic Rousseau, Anne-Mieke Vandamme, Kristel Van Laethem
Pages: 310 - 318 - Predicting aggregation-prone sequences in proteins(2014)
Authors: Greet De Baets, Joost Schymkowitz, Frederic Rousseau
Pages: 41 - 52
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)