Researcher
Francis Impens
- Keywords (Ghent University):post-translational modifications, proteomics, listeria, host-pathogen interactions
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics, (Bio)molecular modelling and design, Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Epigenomics, Environmental safety and health of nanotechnology, Medical biophysics, Adaptive immunology, Cell death, Behavioural neuroscience, Cancer biology
- Disciplines (Ghent University):Infectious diseases, Proteomics, Posttranslational modifications, Proteins, Medical proteomics
- See also: Francis Impens (Flanders Institute for Biotechnology)
Affiliations
- VIB-UGent Center for Medical Biotechnology (Research Center)
Responsible
From1 Oct 2021 → Today - VIB Proteomics Core (Core Lab)
Responsible
From1 Oct 2021 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Impens Lab (Research group)
Responsible
From1 Jan 2017 → Today - VIB Proteomics Core (Core Lab)
Responsible
From1 Jan 2017 → Today - Department of Biochemistry (Department)
Member
From1 Oct 2005 → 30 Sep 2018
Projects
1 - 10 of 10
- Characterizing ISG15 conjugation as a molecular signal for protein oligomerization and translocation in host immunityFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Vaccine-induced and ISG15-mediated immune responses to Bacterial Infection and Moyamoya DiseaseFrom1 Dec 2022 → TodayFunding: BOF - projects
- BOF ZAP human cellular biochemistryFrom1 Sep 2022 → TodayFunding: BOF - ZAP BOF mandates
- Improved data-driven bioinformatics tools to greatly extend neo- and xeno-epitope landscapes detected by immunopeptidomics.From1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- Exploring nanobodies against Interferon Stimulated Gene 15 (ISG15) to combat autoimmune and infectious diseases.From1 Nov 2020 → TodayFunding: FWO fellowships
- Investigating the effects of regulatory phosphorylation and linear ubiquitination on Pyrin-mediated auto-inflammatory disorders.From1 Oct 2019 → TodayFunding: BOF - projects
- Neuro-TRAFFIC: Integrated platform to validate vesicular trafficking-associated processes in neurodegenerative diseasesFrom1 Jun 2017 → 31 May 2021Funding: FWO Strategic Basic Research (SBO)
- 'BacVirISG15' - in the framework of ERA-NET Infect-ERA JTC 2016. The Interferon Stimulated Gene 15 (ISG15) modification system in host pathogen interactions: mechanisms, technology and translational potential.From1 Apr 2017 → 31 Mar 2020Funding: FWO research project (including WEAVE projects)
- Odysseus F. Impens: Proteomics-based characterization of the protein interplay between pathogenic bacteria and their hostFrom1 Oct 2016 → 30 Sep 2021Funding: BOF - Doctoral projects
Publications
31 - 40 of 50
- Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli
Authors: Francis Impens, L Radoshevich, P Cossart, D Ribet
Pages: 12432 - 12437 - An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates (vol 37, pg 21.e1, 2020)
Authors: Jermaine Goveia, Katerina Rohlenova, Federico Taverna, Lucas Treps, Lena-Christin Conradi, Andreas Pircher, Vincent Geldhof, Laura P. M. H. de Rooij, Joanna Kalucka, Liliana Sokol, et al.
Pages: 421 - 421 - Mycolactone subverts immunity by selectively blocking the Sec61 translocon
Authors: L Baron, AO Paatero, JD Morel, Francis Impens, L Guenin-Macé, S Saint-Auret, N Blanchard, R Dillmann, F Niang, S Pellegrini, et al.
Pages: 2885 - 2896 - Protein processing characterized by a gel-free proteomics approach
Authors: Francis Impens, Joël Vandekerckhove, Julie D. Thompson, Christine Schaeffer-Reiss, Marius Ueffing
Pages: 245 - 262 - Mechanisms of congenital heart disease caused by NAA15 haploinsufficiency
Authors: Tarsha L. Ward, Warren Tai, Sarah U. Morton, Francis Impens, Delphi Van Haver, Evy Timmerman, Gabriela Venturini, Kehan Zhang, Min Young Jang, Jon A. L. Willcox, et al.
Pages: 1156 - 1169 - Mapping proteolytic processing in the secretome of gastric cancer-associated myofibroblasts reveals activation of MMP-1, MMP-2, and MMP-3
Authors: Christopher Holmberg, Bart Ghesquière, Francis Impens, J Dinesh Kumar, Nicole Cash, Sandhir Kandola, Peter Hegyi, Timothy C Wang, Graham J Dockray, Andrea Varro
Pages: 3413 - 3422 - Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling.Volume: 18
Authors: Mikhail Steklov, Silvia Pandolfi, Maria Francesca Baietti, Paolo Carai, Mingzhen Zhang, Hyunbum Jang, Yanyan Cai, Eric Legius, Jan Tavernier, Francis Impens, et al.
Pages: 39 - 39 - m-Calpain activation in vitro does not require autolysis or subunit dissociation
Authors: Jordan S Chou, Francis Impens, Peter L Davies
Pages: 864 - 872 - ISG15 counteracts Listeria monocytogenes infection
Authors: L Radoshevich, Francis Impens, D Ribet, JJ Quereda, T Nam Tham, MA Nahori, H Bierne, O Dussurget, J Pizarro-Cerdá, KP Knobeloch, et al.
- A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection
Authors: Haig A. Eskandarian, Francis Impens, Marie-Anne Nahori, Guillaume Soubigou, Jean-Yves Coppée, Pascale Cossart, Melanie A. Hamon