Researcher
Annemieke Madder
- Keywords:protein modification, peptides, oligonucleotides, bioorthogonal conjugation
- Disciplines:Organic chemical synthesis, Food chemistry, Bio-organic chemistry, Drug discovery and development not elsewhere classified, Biomolecular modelling and design, Medicinal and biomolecular chemistry not elsewhere classified
Affiliations
- Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 1993 → Today
Projects
21 - 30 of 61
- Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciencesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthetic antibodies (SynAbs) for detection of cyclodepsipeptide toxins in foodFrom1 Feb 2020 → TodayFunding: IOF - technology validation in real environment
- MEFuranFrom1 Dec 2019 → 31 Jan 2021Funding: IOF - technology concept exploration
- Engineering and study of peptide-based hydrogels for the sustained release of therapeutic proteins.From1 Nov 2019 → 28 Oct 2023Funding: FWO Strategic Basic Research Grant
- Molecular engineering of peptide-based hydrogels for sustained drug releaseFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- MOLECULAR DESIGN OF ‘FROZEN’ APTAMERS: Aptamers with enhanced properties by covalent and non-covalent stabilization using functionalized nucleotides: a combined modelling, NMR and electrochemistry approachFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- MEMCLIP: A comprehensive chemical-biology approach to understand the bioactivity of Pseudomonas cyclic lipopeptides on eukaryotic membranesFrom1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Chemical and enzymatic bioconjugation for the site-specific decoration of proteins with therapeutic property enhancing moietiesFrom1 Oct 2018 → 30 Sep 2022Funding: BOF - Doctoral projects
- LC-'Single Quadrupole MS' for analysis of reaction mixtures and organic compounds with determination of their molecular mass and purity.From1 Jun 2018 → 31 May 2020Funding: BOF - Other initiatives
- Synthesis of furan-modified nucleic acid probes for the development
of new RNA target identification strategies.From1 Jan 2018 → 21 Jul 2021Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 239
- A red light-triggered chemical tool for sequence-specific alkylation of G-quadruplex and I-motif DNA(2023)
Authors: Enrico Cadoni, Lessandro De Paepe, Gertjan Colpaert, Ruben Tack, Dries Waegeman, Alex Manicardi, Annemieke Madder
Pages: 4112 - 4125 - Unlocking the secrets of aptamer-small molecule complexes through NMR spectroscopy(2023)
Authors: Sofie Schellinck, Nataša Medved, Dieter Buyst, Karolien De Wael, Annemieke Madder, Janez Plavec, José Martins
Number of pages: 1 - Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions(2023)
Authors: Helena Braet, Peter-Paul Fransen, Yong Chen, Simon Van Herck, Remco Mariën, Valérie Vanhoorne, Wim Ceelen, Annemieke Madder, Steven Ballet, Richard Hoogenboom, et al.
Pages: 138 - 150 - Acid‐resistant BODIPY amino acids for peptide‐based fluorescence imaging of GPR54 receptors in pancreatic islets(2023)
Authors: Lorena Mendive-Tapia, Laia Miret Casals, Nicole Barth, Jinling Wang, Anne de Bray, Massimiliano Beltramo, Vincent Robert, Christophe Ampe, David Hodson, Annemieke Madder, et al.
- Complex electrostatic effects on the selectivity of membrane-permeabilizing cyclic lipopeptides(2023)
Authors: Jessica Steigenberger, Yentl Verleysen, Niels Geudens, Annemieke Madder, José Martins, Heiko Heerklotz
Pages: 950 - 963 - Photo-induced crosslinking uncovers an antiparallel strand orientation in heterodimeric (EIAALEK)(3)/(KIAALKE)(3) and (EIAALEK)(3)/(RIAALRE)(3) coiled-coil systems(2023)
Authors: Dorien Aerssens, Laia Miret Casals, D. Gomez, D. Sousa-Neves, Y. Levy, M. De Vleesschouwer, Alex Manicardi, Annemieke Madder
Pages: 5648 - 5657 - Host miRNAs as biomarkers of SARS-CoV-2 infection : a critical review(2023)
Authors: Kato Pollet, Nathalie Garnier, Sabine Szunerits, Annemieke Madder, Didier Hober, Ilka Engelmann
Pages: 12 - 35 - Cell surface biotinylation using furan cross-linking chemistry(2023)Series: Methods in Molecular Biology
Authors: Laia Miret Casals, Annemieke Madder
Pages: 11 - 21 - Towards a molecular understanding of the membrane altering properties of viscosin, a cyclic lipodepsipeptide(2022)Volume: 121
Authors: Vic De Roo, Niels Geudens, Yentl Verleysen, Tzong Hsien Lee, Annemieke Madder, Marie-Isabel Aguilar, José Martins
Pages: 162a - 162a - Triazolinedione protein modification : from an overlooked off-target effect to a tryptophan-based bioconjugation strategy(2022)
Authors: Klaas Decoene, Kamil Ünal, An Staes, Jan Gettemans, Johan Winne, Annemieke Madder
Pages: 5390 - 5397
Patents
1 - 10 of 10
- Hydrogel-forming composition for controlled released (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Hydrogel-forming peptides (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- Hydrogel-forming peptides (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Synthetic receptors for ionophoric compounds (Inventor)