Organisation
Liver Connexin and Pannexin Research Group
Research Group
The research topic of LCPR is the study of the use of connexins and pannexins as drug targets and biomarkers for the therapy and diagnosis of acute and chronic liver disease.
Projects
1 - 7 of 7
- H2020: Ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessmentFrom1 May 2021 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- Cellular communication as target and biomarker in liver disease and toxicity: from basic research towards clinical applicationFrom1 Jan 2021 → TodayFunding: BOF - Methusalem
- Production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases.From1 Mar 2020 → TodayFunding: H2020-EU.1.2.- EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
- GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety.From1 Jan 2020 → TodayFunding: IOF - technology concept exploration, IOF - mandates
- CONNECT-2-CLINIC: Connexin and pannexin peptidomimetics and nanobodies for the clinical treatment of liver disease.From1 Jan 2020 → 31 Dec 2021Funding: H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
- Connexin hemichannels and pannexin channels as mediators and in vitro indicators of drug-induced cholestatic liver injury.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Are connexins, pannexins and their (hemi)channels novel biomarkers and pharmacological targets in the prognosis and therapy of liver cancer? (Toekenning in het kader van bilaterale onderzoekssamenwerking met Brazilië)From1 Jan 2019 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
Publications
31 - 40 of 98
- Connexins and their channels in inflammation(2016)
Authors: Joost Willebrords, Sara Crespo Yanguas, Michael Maes, Elke Decrock, Nan Wang, Luc Leybaert, Brenda R. Kwak, Colin R. Green, Bruno Cogliati, Mathieu Vinken
Pages: 413-439 - Biomarkers of cholestasis(2021)
Authors: Alanah Pieters, Eva Gijbels, Bruno Cogliati, Pieter Annaert, Lindsey Devisscher, Mathieu Vinken
Pages: 437-454 - Inhibitors of connexin and pannexin channels as potential therapeutics(2017)
Authors: Joost Willebrords, Michael Maes, Sara Crespo Yanguas, Mathieu Vinken
Pages: 144-160 - The dual face of connexin-based astroglial Ca(2+) communication(2014)
Authors: Marijke De Bock, Elke Decrock, Nan Wang, Mélissa Bol, Mathieu Vinken, Geert Bultynck, Luc Leybaert
Pages: 2211-2232 - Screening of repeated dose toxicity data in safety evaluation reports of cosmetic ingredients issued by the Scientific Committee on Consumer Safety between 2009 and 2019(2020)
Authors: Emma Arnesdotter, Christophe Debruyne, Olga De Troyer, Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke
Pages: 3723-3735 - Alcohol intake and cancer risk, in: Nutrition and Cancer Prevention.(2019)
Authors: Mathieu Vinken
Pages: 108-127Number of pages: 19 - Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction(2016)
Authors: Danny Bavli, Sebastian Prill, Elishai Ezra, Gahl Levy, Merav Cohen, Mathieu Vinken, Jan Vanfleteren, Magnus Jaeger, Yaakov Nahmias
Pages: E2231-E2240 - What is understood by “animal-free research”?(2019)
Authors: Stina Oredsson, S. Coecke, J. van der Valk, Mathieu Vinken
Pages: 143-144 - Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis(2019)
Authors: Guilherme Ribeiro Romualdo, Ariane Bartolomeu Rocha, Mathieu Vinken, Bruno Cogliati, Fernando Salvador Moreno, María Angel García Chaves, Luis Fernando Barbisan
Pages: 567-589 - Mode-of-action working group: capturing mode-of-action knowledge(2015)Volume: 5
Authors: Brigitte Landesmann, Mathieu Vinken
Pages: 296-299