Organisation
Liver Connexin and Pannexin Research Group
Research Group
The research topic of LCPR is the study of the use of connexins and pannexins as drug targets and biomarkers for the therapy and diagnosis of acute and chronic liver disease.
Projects
1 - 7 of 7
- H2020: Ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk assessmentFrom1 May 2021 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- Cellular communication as target and biomarker in liver disease and toxicity: from basic research towards clinical applicationFrom1 Jan 2021 → TodayFunding: BOF - Methusalem
- Production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases.From1 Mar 2020 → TodayFunding: H2020-EU.1.2.- EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
- GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety.From1 Jan 2020 → TodayFunding: IOF - technology concept exploration, IOF - mandates
- CONNECT-2-CLINIC: Connexin and pannexin peptidomimetics and nanobodies for the clinical treatment of liver disease.From1 Jan 2020 → 31 Dec 2021Funding: H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
- Connexin hemichannels and pannexin channels as mediators and in vitro indicators of drug-induced cholestatic liver injury.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Are connexins, pannexins and their (hemi)channels novel biomarkers and pharmacological targets in the prognosis and therapy of liver cancer? (Toekenning in het kader van bilaterale onderzoekssamenwerking met Brazilië)From1 Jan 2019 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 98
- EFFECTS OF TRICHOSTATIN A ON DRUG UPTAKE TRANSPORTERS IN PRIMARY RAT HEPATOCYTE CULTURES(2015)
Authors: Eva Ramboer, Tamara Vanhaecke, Vera Rogiers, Mathieu Vinken
Pages: 567-576 - Cell junctions and oral health(2019)
Authors: Mohammad Samiei, Elham Ahmadian, Aziz Eftekhari, Mohammad Ali Eghbal, Fereshte Rezaie, Mathieu Vinken
Pages: 317-330 - Testing in vitro tools for the prediction of cholestatic liver injury induced by non-pharmaceutical chemicals(2021)
Authors: Eva Gijbels, Lindsey Devisscher, Mathieu Vinken
- Mechanisms and in vitro models of drug-induced cholestasis(2019)
Authors: Eva Gijbels, Vânia Vilas-Boas, Neel Deferm, Lindsey Devisscher, Jaeschke Hartmut, Pieter Annaert, Mathieu Vinken
Pages: 1169-1186 - Roles of connexins and pannexins in digestive homeostasis(2015)
Authors: Michael Maes, Bruno Cogliati, Sara Crespo Yanguas, Joost Willebrords, Mathieu Vinken
Pages: 2809-2821 - Erratum to(2017)
Authors: Michael Maes, Mitchell R. Mcgill, Tereza Cristina da Silva, Chloé Abels, Margitta Lebofsky, James L Weemhoff, Taynã Tiburcio, Isabel Veloso Alves Pereira, Joost Willebrords, Sara Crespo Yanguas, et al.
Pages: 2263-2264 - Canonical and non-canonical roles of connexin43 in cardioprotection(2020)
Authors: Olga M. Rusiecka, Jade Montgomery, Sandrine Morel, Daniela Batista-Almeida, Raf Van Campenhout, Mathieu Vinken, Henrique Girao, Brenda R. Kwak
- In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic Approach(2021)
Authors: Andres Tabernilla Garcia, Bruna dos Santos Rodrigues, Alanah Pieters, Anne Caufriez, Kaat Leroy, Raf Van Campenhout, Axelle Cooreman, Ana Rita Coelho Gomes, Emma Arnesdotter, Eva Gijbels, et al.
Pages: 1-45 - Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction(2016)
Authors: Danny Bavli, Sebastian Prill, Elishai Ezra, Gahl Levy, Merav Cohen, Mathieu Vinken, Jan Vanfleteren, Magnus Jaeger, Yaakov Nahmias
Pages: E2231-E2240 - Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice(2017)
Authors: Joost Willebrords, Bruno Cogliati, Isabel Veloso Alves Pereira, Tereza Cristina da Silva, Sara Crespo Yanguas, Michael Maes, Veronica Mollica Govoni, Elke Decrock, Marina S. Nogueira, Inar A. de Castro, et al.