Publicaties
New Perspectives on the Immunopathogenesis and Treatment of Uveitis Associated With Vogt-Koyanagi-Harada Disease KU Leuven
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy Instituut voor Tropische Geneeskunde
Infantile-onset RNaseT2 deficient leukoencephalopathy is characterised by cystic brain lesions, multifocal white matter alterations, cerebral atrophy, and severe psychomotor impairment. The phenotype is similar to congenital cytomegalovirus brain infection and overlaps with type I interferonopathies, suggesting a role for innate immunity in its pathophysiology. To date, pathophysiological studies have been hindered by the lack of mouse models ...
Harvesting and dewatering of high-productivity bulk microalgae systems KU Leuven
Pat1b and LSm14 PROTEINS: regulators of neuronal mRNA metabolism with a possible role in Spinal Muscular Atrophy KU Leuven
Evolution and systematic value of leaf crystal macropatterns in the genus Peperomia (Piperaceae) Universiteit Gent
Attachment of the outer membrane lipoprotein (OprI) of Pseudomonas aeruginosa to the mucosal surfaces of the respiratory and digestive tract of chickens Vrije Universiteit Brussel
Neutrophil extracellular traps in cardiac fibrosis - Peptidylarginine deiminase 4 and neutrophil extracellular traps in chronic inflammation and cardiac fibrosis KU Leuven
The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella KU Leuven
Main path and byways Vrije Universiteit Brussel
System xc (-) is a cystine/glutamate antiporter that exchanges extracellular cystine for intracellular glutamate. Cystine is intracellularly reduced to cysteine, a building block of GSH. As such, system xc (-) can regulate the antioxidant capacity of cells. Moreover, in several brain regions, system xc (-) is the major source of extracellular glutamate. As such this antiporter is able to fulfill key physiological functions in the CNS, while ...