Publicaties
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A hairy-root transformation protocol for Trigonella foenum-graecum L. as a tool for metabolic engineering and specialised metabolite pathway elucidation. Vlaams Instituut voor Biotechnologie Universiteit Gent
Metabolic engineering and metabolic modeling of Escherichia coli for the production of chemicals from renewable resources (MEMORE) Universiteit Gent
Engineering the plant metabolic system by exploiting metabolic regulation. Vlaams Instituut voor Biotechnologie
Metabolic engineering and metabolic modeling of Escherichia coli for the production of chemicals from renewable resources (MEMORE) Universiteit Gent
Metabolic Characterization and Engineering of Streptomyces lividans Producing Heterologous Proteins (Metabole karakterisering en engineering van Streptomyces lividans voor heterologe eiwitproductie) KU Leuven
Streptomycetes have become attractive hosts for heterologous protein production due to for instance, their ability to efficiently secrete their proteins in the extracellular environment. Among these microbes, Streptomyces lividans, known to have a reduced restriction-modification barrier, has been used more extensively for heterologous protein production. Hitherto, studies on metabolic characterization and engineering of S. lividans for ...
Metabolic engineering and modelling of Escherichia coli for the production of succinate Universiteit Gent
Current climate issues and the ongoing depletion of oil reserves have led to an increased attention for biobased production processes. Not only the production of bio-energy but also biochemicals have gained interest. Recent reports of the US department of energy and the GROWTH program of the European commission review a comprehensive list of chemicals that can be produced via biological processes and which may be of great importance to sustain a ...
Engineering complex metabolic pathways in plants Universiteit Gent
Modeling with a view to target identification in metabolic engineering : a critical evaluation of the available tools Universiteit Gent
Validation study of 24 deepwell microtiterplates to screen libraries of strains in metabolic engineering. Vrije Universiteit Brussel
In this study we validated the use of 24 square deepwell microtiterplates to screen large libraries of metabolically engineered strains by investigating the optimization of succinate production. Wild type E. coli MG1655 and 11 derived mutants were physiologically evaluated by growth in 24 deepwell MTPs and 2L benchtop bioreactors. Growth parameters, product yields and byproduct formation were determined for all mutants. The results show that ...