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Expression and Localization of Angiogenic Growth Factors in Developing Porcine Mesonephric Glomeruli KU Leuven Universiteit Gent Universiteit Antwerpen
The development and growth of renal glomeruli is regulated by specific angiogenic growth factors, including vascular endothelial growth factor (VEGF) and the angiopoietins (ANGPT1 and ANGPT2). The expression of these factors has already been studied during metanephric glomerulogenesis, but it remains to be elucidated during the development of the embryonic mesonephros, which can function as an interesting model for glomerular development and ...
Quantitative mRNA expression analysis in kidney glomeruli using microdissection techniques KU Leuven Universiteit Gent
The introduction of new tools for molecular analysis, such as RT-qPCR and microarrays, has provided researchers with powerful applications to study renal disease and development. However, the high cellular heterogeneity of the renal tissue complicates the molecular analysis of specific cells and cell groups such as glomerular or tubular cells. In the past, glomerular sieving and manual dissection were used for the isolation of glomeruli. ...
Intussusceptive pillar formation in developing porcine glomeruli Universiteit Gent
Expression of angiogenic growth factors in porcine mesonephric glomeruli, isolated with Laser Capture Microdissection Universiteit Gent
Stereological and immunogold studies on TIE1 and TIE2 localization in glomeruli indicate angiopoietin signaling in podocytes Universiteit Gent
Simplified methods for estimating glomerular filtration rate in cats and for detection of cats with low or borderline glomerular filtration rate Universiteit Gent
Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium. Vlaams Instituut voor Biotechnologie KU Leuven
The Predictive Value of Glomerular Filtration Rate-Based Scaling of Pediatric Clearance and Doses for Drugs Eliminated by Glomerular Filtration with Varying Protein-Binding Properties KU Leuven
INTRODUCTION: For drugs eliminated by glomerular filtration (GF), clearance (CL) is determined by GF rate (GFR) and the unbound fraction of the drug. When predicting CL of GF-eliminated drugs in children, instead of physiologically based pharmacokinetic (PBPK) methods that consider changes in both GFR and protein binding, empiric bodyweight-based methods are often used. In this article, we explore the predictive value of scaling using a GFR ...