Publicaties
The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017 Universiteit Antwerpen
Sofosbuvir in Combination with Simeprevir +/- Ribavirin in Genotype 4 Hepatitis C Patients with Advanced Fibrosis or Cirrhosis Vrije Universiteit Brussel KU Leuven Universiteit Antwerpen
INTRODUCTION: Hepatitis C virus (HCV) is a major global health issue and successful treatment has been associated with a reduction of risk of all-cause mortality. Advancements have been made in HCV treatment through the use of interferon-free regimens. Most trials have been conducted in HCV genotype (GT) 1 and data for interferon-free regimens in GT4 patients are limited. The aim of this study was to evaluate the safety and efficacy of ...
A Multi-level Modeling Framework to Study Hepatic Perfusion Characteristics in case of Liver Cirrhosis KU Leuven Universiteit Gent
A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance Universiteit Gent
High prevalence of diabetes mellitus in patients with liver cirrhosis Vrije Universiteit Brussel
The reported prevalence of Type 2 diabetes mellitus in patients with liver cirrhosis is five times higher than in the general population. However, these data were never adjusted for classical risk factors for Type 2 diabetes. We therefore investigated the association between cirrhosis and Type 2 diabetes and adjusted for known risk factors for Type 2 diabetes.
Methods
We reviewed medical files for ...
Serological response and breakthrough infection after COVID-19 vaccination in patients with cirrhosis and post-liver transplant Vrije Universiteit Brussel Universiteit Gent
BACKGROUND: Vaccine hesitancy and lack of access remain major issues in disseminating COVID-19 vaccination to liver patients globally. Factors predicting poor response to vaccination and risk of breakthrough infection are important data to target booster vaccine programs. The primary aim of the current study was to measure humoral responses to 2 doses of COVID-19 vaccine. Secondary aims included the determination of factors predicting ...
Liver cirrhosis and thyroid function: Friend or foe? Vrije Universiteit Brussel
INTRODUCTION: The liver plays a central role in thyroid hormone metabolism, transport, and clearance. A normal function of both the thyroid gland and the liver is therefore necessary to maintain normal thyroid hormone levels and action. Data regarding thyroid function in patients with liver cirrhosis are scarce and variable. The most consistent finding is a decreased free triiodothyronine (fT3) level, which correlates with the severity of ...
Diabetes mellitus and cirrhosis of the liver: a prognostically unfavourable combination Vrije Universiteit Brussel
Socioeconomic inequalities in chronic liver diseases and cirrhosis mortality in european urban areas before and after the onset of the 2008 economic recession Vrije Universiteit Brussel
Objective: To analyse the trends in chronic liver diseases and cirrhosis mortality, and the associated socioeconomic inequalities, in nine European cities and urban areas before and after the onset of the 2008 financial crisis. Methods: This is an ecological study of trends in three periods of time: two before (2000–2003 and 2004–2008), and one after (2009–2014) the onset of the economic crisis. The units of analysis were the geographical ...