Publicaties
Convergent evolution of water-conducting cells in Marchantia recruited the ZHOUPI gene promoting cell wall reinforcement and programmed cell death. Vlaams Instituut voor Biotechnologie
Current Status of Human Adipose-Derived Stem Cells: Differentiation into Hepatocyte-Like Cells Vrije Universiteit Brussel
Train your T cells: How skeletal muscles and T cells keep each other fit during aging Universiteit Hasselt
Tenofovir diphosphate and emtricitabine triphosphate concentrations in blood cells compared with isolated peripheral blood mononuclear cells: a new measure of antiretroviral adherence? Instituut voor Tropische Geneeskunde
Evaluation of the multipotent character of human adipose derived stem cells isolated by Ficoll gradient centrifugation and red blood cell lysis treatment Vrije Universiteit Brussel
No significant difference in the genotypic expression of the multipotent markers octamer binding ...
Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells Instituut voor Tropische Geneeskunde Universiteit Antwerpen
Success of dendritic cell (DC) therapy in treating malignancies is depending on the DC capacity to attract immune effector cells, considering their reciprocal crosstalk is partially regulated by cell-contact-dependent mechanisms. Although critical for therapeutic efficacy, immune cell recruitment is a largely overlooked aspect regarding optimization of DC vaccination. In this paper we have made a head-to-head comparison of interleukin ...
Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells Vrije Universiteit Brussel
Adult neural stem cell proliferation is dynamic and has the potential for massive self-renewal yet undergoes limited cell division in vivo. Here, we report an epigenetic mechanism regulating proliferation and self-renewal. The recruitment of the PI3K-related kinase signaling pathway and histone H2AX phosphorylation following GABA(A) receptor activation limits subventricular zone proliferation. As a result, NSC self-renewal and niche size is ...