Publicaties
Gekozen filters:
Gekozen filters:
Pitfalls of rubella serology while on the brink of elimination : evaluation of national data, Belgium, 2017 Universiteit Gent KU Leuven Instituut voor Tropische Geneeskunde
Background: In Belgium, rubella serology is frequently requested in women of childbearing age, despite high vaccination coverage and a near-absence of congenital rubella cases. Different test kits are available and should be standardised by an international standard preparation. Aim: To analyse and compare rubella serology practices in Belgian laboratories. Methods: As part of the mandatory External Quality Assessment programme for rubella ...
Hepatitis E virus serology and PCR: does the methodology matter? Universiteit Hasselt Universiteit Gent
Hepatitis E virus (HEV) genotype 3 is an emerging pathogen in the developed world. As the clinical manifestations and routine laboratory parameters are often nonspecific, accurate diagnostic tests are crucial. In the current study, the performance of six serological assays and three PCR assays for the detection of HEV was evaluated. In the setting of the Ghent University Hospital, patients with clinically suspected HEV infection were tested for ...
Infective endocarditis caused by Neisseria mucosa on a prosthetic pulmonary valve with false positive serology for Coxiella burnetii - the first described case Instituut voor Tropische Geneeskunde
We present a case of infective endocarditis (IE) on a prosthetic pulmonary valve in a 36-year-old patient with tetralogy of Fallot (TOF). The patient underwent valve replacement surgery and active antibiotic treatment against Gram-negative cocci (Piperacillin Tazobactam then Ceftriaxone) for a total duration of 42 days with a favourable outcome. The causative agent was Neisseria mucosa which was identified on the infected valve by sequencing ...
Confusing mumps serology during an outbreak Universiteit Gent Universiteit Hasselt
Serology indicates cytomegalovirus infection is associated with varicella-zoster virus reactivation Universiteit Hasselt Universiteit Antwerpen
Varicella-zoster virus (VZV) causes chickenpox after which the virus remains latent in neural ganglia. Subsequent reactivation episodes occur, leading mainly to subclinical detection of VZV, but also to the clinical entity herpes zoster. These reactivations are known to occur most frequently amongst immunocompromised individuals, but the incidence of herpes zoster is also known to increase with age, supposedly as a consequence of ...
False positive Herpes Simplex IgM serology in COVID-19 patients correlates with SARS-CoV-2 IgM/IgG seropositivity Universiteit Antwerpen
Differentiating COVID-19 from other causes of viral pneumonia, like herpes simplex (HSV), can be complicated by shared clinical and laboratory features. Viral pneumonia is mostly diagnosed based on molecular or serological techniques. Serological immunoassay interferences, often attributed to concurrent appearance of heterologous (viral) immunoglobulins, is well-known, but has not been studied in COVID-19 patients. Following false positive HSV ...
Group A rotaviruses in Chinese bats: genetic composition, serology, and evidence for bat-to-human transmission and reassortment KU Leuven
Bats are natural reservoirs for many pathogenic viruses, and increasing evidence supports the notion that bats can also harbor group A rotaviruses (RVAs), important causative agents of diarrhea in children and young animals. Currently, 8 RVA strains possessing completely novel genotype constellations or genotypes possibly originating from other mammals have been identified from African and Chinese bats. However, all the data were mainly based on ...
Hepatitis E virus serology and PCR : does the methodology matter? Universiteit Gent
Circulating human microRNAs are not linked to JC polyomavirus serology or urinary viral load in healthy subjects KU Leuven
BACKGROUND: JC polyomavirus (JCPyV) is a widespread human polyomavirus that usually resides latently in its host. It can be reactivated under immunomodulating conditions and cause Progressive Multifocal Leukoencephalopathy (PML). Circulating microRNAs (miRNAs) are emerging as promising biomarkers for several pathologies. In this study, we have investigated whether circulating miRNAs exist that are differentially expressed between JCPyV ...