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Regulated cell death and its role in Alzheimer's disease and amyotrophic lateral sclerosis. KU Leuven
Despite considerable research efforts, it is still not clear which mechanisms underlie neuronal cell death in neurodegenerative diseases. During the last 20 years, multiple pathways have been identified that can execute regulated cell death (RCD). Among these RCD pathways, apoptosis, necroptosis, pyroptosis, ferroptosis, autophagy-related cell death, and lysosome-dependent cell death have been intensively investigated. Although RCD consists of ...
How do we fit ferroptosis in the family of regulated cell death? Vlaams Instituut voor Biotechnologie Universiteit Antwerpen Universiteit Gent
The molecular machinery of regulated cell death Vlaams Instituut voor Biotechnologie Universiteit Antwerpen Universiteit Gent
Regulated Cell Death as a Therapeutic Target for Novel Antifungal Peptides and Biologics KU Leuven
The rise of microbial pathogens refractory to conventional antibiotics represents one of the most urgent and global public health concerns for the 21st century. Emergence of Candida auris isolates and the persistence of invasive mold infections that resist existing treatment and cause severe illness has underscored the threat of drug-resistant fungal infections. To meet these growing challenges, mechanistically novel agents and strategies are ...
The potential role of regulated cell death in dry eye diseases and ocular surface dysfunction Universiteit Antwerpen
The research on new treatments for dry eye diseases (DED) has exponentially grown over the past decades. The increased prevalence of dry eye conditions, particularly in the younger population, has received much attention. Therefore, it is of utmost importance to identify novel therapeutical targets. Regulated cell death (RCD) is an essential process to control the biological homeostasis of tissues and organisms. The identification of different ...