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Population genomic evidence of structured and connected Plasmodium vivax populations under host selection in Latin America Instituut voor Tropische Geneeskunde
Pathogen genomic epidemiology has the potential to provide a deep understanding of population dynamics, facilitating strategic planning of interventions, monitoring their impact, and enabling timely responses, and thereby supporting control and elimination efforts of parasitic tropical diseases. Plasmodium vivax, responsible for most malaria cases outside Africa, shows high genetic diversity at the population level, driven by factors like ...
Genetic diversity and population structure in contemporary house sparrow populations along an urbanization gradient Universiteit Gent
[Comorbid anxiety disorders and alcohol-related disorders in a population of bipolar I disorder: investigation in a Flemish population] KU Leuven
BACKGROUND: Bipolar I disorder (bp i) is a very debilitating psychiatric disorder which is frequently associated with comorbid psychiatric and somatic disorders. Many studies in other countries show strongly elevated prevalences of anxiety disorders and alcohol-related disorders in the bp i population, but so far no data on this topic are available with regard to the Flemish population. AIM: To determine the prevalence of anxiety disorders and ...
EPH83 AN ONE-YEAR STATIC CROSS-SECTIONAL POPULATION MODEL TO ASSESS THE INFECTION BURDEN ACROSS THE AGEING POPULATION: AN APPLICATION TO THE FLEMISH COUNTY Universiteit Hasselt
diabetes, depression and vehicle-related accidents. Prevalence and incidence data for OSA and comorbidities, as well as Australian specific labour data was extracted from published sources. To test the effect of a hypothetical intervention, a second cohort was then modelled assuming a 15% reduction in OSA prevalence and a 10% reduction in comorbidities in OSA patients. Results: Over a lifetime, Australian population with OSA accrued 262,659,069 ...
Rapid evolution leads to differential population dynamics and top-down control in resurrected Daphnia populations KU Leuven
There is growing evidence of rapid genetic adaptation of natural populations to environmental change, opening the perspective that evolutionary trait change may subsequently impact ecological processes such as population dynamics, community composition, and ecosystem functioning. To study such eco-evolutionary feedbacks in natural populations, however, requires samples across time. Here, we capitalize on a resurrection ecology study that ...
The Use of Mechanistic Population Models in Metal Risk Assessment: Combined Effects of Copper and Food Source on Lymnaea stagnalis Populations KU Leuven Universiteit Gent
Environmental risk assessment (ERA) of chemicals aims to protect populations, communities, and ecosystems. Population models are considered more frequent in ERA because they can bridge the gap between the individual and the population level. Lymnaea stagnalis (the great pond snail) is an organism that is particularly sensitive to various metals, including copper (Cu). In addition, the sensitivity of this species to Cu differs between food ...
Mycorrhizal diversity, seed germination and long-term changes in population size across nine populations of the terrestrial orchid Neottia ovata KU Leuven
In plant species that rely on mycorrhizal symbioses for germination and seedling establishment, seedling recruitment and temporal changes in abundance can be expected to depend on fungal community composition and local environmental conditions. However, disentangling the precise factors that determine recruitment success in species that critically rely on mycorrhizal fungi represents a major challenge. In this study, we used seed germination ...
Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy Instituut voor Tropische Geneeskunde Universiteit Gent
Due to the highly restricted species-tropism of Hepatitis C virus (HCV) a limited number of animal models exist for pre-clinical evaluation of vaccines and antiviral compounds. The human-liver chimeric mouse model allows heterologous challenge with clinically relevant strains derived from patients. However, to date, the transmission and longitudinal evolution of founder viral populations in this model have not been characterized in-depth ...
Seed limitation restricts population growth in shaded populations of a perennial woodland orchid KU Leuven
Seed production and seedling recruitment are thought to be of minor importance in determining population dynamics and long-term viability in long-lived perennial plants. Seed addition experiments, on the other hand, have amply shown that supplemental addition of seeds almost always, irrespective of longevity, results in increased seedling recruitment. Any change in the environment that affects fruit and seed production can thus be expected to ...