Publicaties
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The complex intron landscape and massive intron invasion in a picoeukaryote provides insights into intron evolution Universiteit Gent
PCR survey of 50 introns in animals: cross-amplification of homologous EPIC loci in eight non-bilaterian, protostome and deuterostome phyla Universiteit Gent
Introns reduce transitivity proportionally to their length, suggesting that silencing spreads along the pre-mRNA Universiteit Gent
Group I introns in Staphylococcus bacteriophages KU Leuven
The abundance of group I introns, intragenic RNA sequences capable of self-splicing, in Gram-positive bacteriophage genomes, is illustrated by various new group I introns recently described in Staphylococcus phage genomes. These introns were found to interrupt DNA metabolism genes as well as late genes. These group I introns often code for homing endonucleases, which promote lateral transfer of group I introns, thereby enabling spread through a ...
[ORAL PRESENTATION] Introns and spacers as tools towards resolviIrg the radiation of Rubiaceae Plantentuin Meise / Agentschap Plantentuin Meise
Higher intron loss rate in Arabidopsis thaliana than A. lyrata is consistent with stronger selection for a smaller genome Universiteit Gent
Indirect effect of IGF2 intron3 g.3072G>A mutation on prolificacy in sows KU Leuven
Summary A QTL located in the paternally expressed insulin-like growth factor 2 (IGF2) gene is known to increase muscle growth and reduce fat deposition in pigs. This makes the QTL in IGF2 a good marker for use in pig breeding programmes. However, care has to be taken as it is postulated that increased leanness and lowered fat deposition may have a negative effect on the prolificacy and longevity of sows. Selection of sire and dam lines for ...
Limited MHC class I intron 2 repertoire variation in bonobos Koninklijke Maatschappij voor Dierkunde van Antwerpen Universiteit Antwerpen
Common chimpanzees (Pan troglodytes) experienced a selective sweep, probably caused by a SIV-like virus, which targeted their MHC class I repertoire. Based on MHC class I intron 2 data analyses, this selective sweep took place about 2-3 million years ago. As a consequence, common chimpanzees have a skewed MHC class I repertoire that is enriched for allotypes that are able to recognise conserved regions of the SIV proteome. The bonobo (Pan ...