Investigating drug tolerance in Mycobacterium tuberculosis Instituut voor Tropische Geneeskunde
Annelies Van Rie, Bouke de Jong
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), remains an important global public health problem, with 10 million new cases and 1.6 million TB deaths in 20171. Current TB treatment is suboptimal as patients have to be adherent to ≥6 months treatment with multiple drugs2. This results in long periods of infectiousness, considerable inflammation and lung damage and an increased risk of acquisition of drug ...