Publicaties
Temperature and time dependence on recovery stress relaxation in nickel titanium wire during isothermal holding at high temperatures KU Leuven
Field implementation and evaluation of novel isothermal, nucleic acid–based diagnostic tools for malaria elimination in sub Saharan Africa Instituut voor Tropische Geneeskunde
Diagnostic performance of a novel loop-mediated isothermal amplification (LAMP) assay targeting the apicoplast genome for malaria diagnosis in a field setting in sub-Saharan Africa Instituut voor Tropische Geneeskunde Universiteit Antwerpen KU Leuven
BACKGROUND: New diagnostic tools to detect reliably and rapidly asymptomatic and low-density malaria infections are needed as their treatment could interrupt transmission. Isothermal amplification techniques are being explored for field diagnosis of malaria. In this study, a novel molecular tool (loop-mediated isothermal amplification-LAMP) targeting the apicoplast genome of Plasmodium falciparum was evaluated for the detection of ...
Influence of pre-strain on recovery stress of annealed NiTi thin wire during isothermal holding KU Leuven
Isothermal crystallization study on aqueous solution of poly(vinyl methyl ether) by DSC method KU Leuven
Quantification of isothermal crystallization of polyamide 12: Modelling of crystallization kinetics and phase composition KU Leuven
PIV measurements of isothermal plane turbulent impinging jets at moderate Reynolds numbers KU Leuven
Detection of pathogen-specific antibodies by loop-mediated isothermal amplification Vrije Universiteit Brussel Universiteit Gent
Loop-mediated isothermal amplification (LAMP) is a method for enzymatically replicating DNA that has great utility for clinical diagnosis at the point of care (POC), given its high sensitivity, specificity, speed, and technical requirements (isothermal conditions). Here, we adapted LAMP for measuring protein analytes by creating a protein-DNA fusion (referred to here as a "LAMPole") that attaches oligonucleotides (LAMP templates) to IgG ...
Validation of an apicoplast genome target for the detection of Plasmodium species using polymerase chain reaction and loop mediated isothermal amplification Instituut voor Tropische Geneeskunde KU Leuven Universiteit Antwerpen
The genome of the Plasmodium apicoplast, which has a higher copy number compared with current targets for molecular diagnosis of malaria, appears to be a suitable target for detection of submicroscopic infections that are capable of sustaining transmission. Novel primers targeting a conserved segment of the apicoplast (PFC10_AP|0010:rRNA) were designed and used in a number of different high throughput platforms such as single-step PCR ...