Endocrine Regulatory Mechanisms of Insulin Signaling in the Insulin-Producing Cells of Drosophila melanogaster KU Leuven
Type 2 Diabetes (T2D) and obesity are major health concerns of the modern world affecting approximately 8% and 11% of the global population, respectively, making it a clear medical and economic burden. T2D is a systemic dysfunction characterized by the body's inability to respond to insulin secretion, which is key in maintaining metabolic homeostasis and preventing conditions such as hyperglycemia and glucose intolerance, both of which can lead ...