Pathophysiological endotyping in patients treated with a mandibular advancement device and upper airway stimulation for obstructive sleep apnea Universiteit Antwerpen
Pathophysiology of obstructive sleep apnea can be subdivided into 5 endotypic traits: site of upper airway collapse, loop gain, muscle responsiveness and arousal threshold. Each of these traits can be measured using gold standard techniques, however, these are not available in routine measurements. Currently, only the site of upper airway collapse is assessed in routine clinical practice using drug-induced sleep endoscopy. The 4 other traits are ...