Publicaties

It is generally recommended to perform multiple stool examinations in order to improve the diagnostic accuracy when assessing the impact of mass drug administration programmes to control human intestinal worm infections and determining efficacy of the drugs administered. However, the collection and diagnostic work-up of multiple stool samples increases costs and workload. It has been hypothesized that these increased efforts provide more ...

Although collective efficacy has been demonstrated to be an important precursor of team performance, there remains some ambiguity concerning its assessment. Therefore, the main aim of the present study was to test the validity of previous collective efficacy measures. An online survey was completed by 4, 451 Flemish players and coaches from nine different team sports. The results revealed two distinct and reliable scales; process-oriented ...

Although collective efficacy has been demonstrated to be an important precursor of team performance, there remains some ambiguity concerning its assessment. Therefore, the main aim of the present study was to test the validity of previous collective efficacy measures. An online survey was completed by 4,451 Flemish players and coaches from nine different team sports. The results revealed two distinct and reliable scales; process-oriented ...

The faecal egg count reduction test (FECRT) is the method of choice to monitor anthelmintic efficacy against gastro-intestinal nematodes in livestock. Guidelines on how to conduct a FECRT are made available by the World Association for the Advancement of Veterinary Parasitology (WAAVP). Since the publication of these guidelines in the early 1990s, some limitations have been noted, including (i) the ignorance of host-parasite interactions that ...

Studies have indicated that teacher efficacy influences teachers’ effort to encounter classroom difficulties and students’ academic performances (Fackler & Malmberg, 2016). Through mainly psychological research, we know which teacher characteristics affect teacher efficacy, nevertheless, classroom or school characteristics are largely overlooked in studies on teacher efficacy (Knoblauch & Hoy, 2008). Few studies concerning teacher ...

When used for the evaluation of drug efficacy against Psoroptes ovis, the diagnostic performance of different sampling strategies for a mite count reduction test (MCRT) remains unclear. In the present study, a novel simulation framework was constructed that accounted for relevant biological features of P. ovis infestations in cattle and that was parameterized with field data from 16 farms (154 animals). Second, this framework was applied to ...

Background: Robust reference values for fecal egg count reduction (FECR) rates of the most widely used anthelmintic drugs in preventive chemotherapy (PC) programs for controlling soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and hookworm) are still lacking. However, they are urgently needed to ensure detection of reduced efficacies that are predicted to occur due to growing drug pressure. Here, using a standardized ...

The importance of slow dissociation of non-nucleoside reverse transcriptase inhibitors (NNRTIs) for antiviral effect has been investigated. The kinetic characteristics of a series of NNRTIs interacting with wild type and drug resistant variants of HIV-1 RT (EC 2.7.7.49) were analyzed by SPR biosensor technology. The antiviral effect was determined in MT-4 and peripheral blood mononuclear cells. Due to extremely slow dissociation rates and a ...

Applying post-harvest control measures such as adding mycotoxin detoxifying agents is a frequently-used mitigation strategy for mycotoxins. EFSA states that the efficacy of these detoxifiers needs to be tested using specific biomarkers for exposure. However, the proposed biomarkers for exposure are not further optimized for specific target species. Hence, the goal of this study was (a) to evaluate the most suitable biomarkers for deoxynivalenol ...