Publicaties
Chikungunya virus and West Nile virus infections imported into Belgium, 2007-2012 Instituut voor Tropische Geneeskunde
SUMMARY Arboviral infections are emerging among tourists travelling to (sub)tropical regions. This study aims to describe the importation of chikungunya virus (CHIKV) and West Nile virus (WNV) into Belgium over a 6-year period from 2007 to 2012. Clinical samples were obtained from travellers presenting at the outpatient clinic of the Institute of Tropical Medicine (ITM), Antwerp, Belgium or submitted to the Central Laboratory for Clinical ...
GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 2: Epidemiological distribution of o'nyong-nyong virus KU Leuven
The CD147 protein complex is involved in entry of Chikungunya virus and related alphaviruses in human cells Universiteit Gent Instituut voor Tropische Geneeskunde Universiteit Antwerpen
A Chikungunya virus trans-replicase system reveals the importance of delayed nonstructural polyprotein processing for efficient replication complex formation in mosquito cells Instituut voor Tropische Geneeskunde Universiteit Antwerpen
Chikungunya virus (CHIKV) is a medically important alphavirus that is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. The viral replicase complex consists of four nonstructural proteins (nsPs) expressed as a polyprotein precursor and encompasses all enzymatic activities required for viral RNA replication. nsPs interact with host components of which most are still poorly understood, especially in mosquitos. A CHIKV ...
A reassessment of mycophenolic acid as a lead compound for the development of inhibitors of chikungunya virus replication KU Leuven
Antiviral strategies against Chikungunya virus KU Leuven
Diagnostic accuracy of a rapid E1-antigen test for chikungunya virus infection in a reference setting Universiteit Antwerpen KU Leuven Instituut voor Tropische Geneeskunde
Chikungunya virus infection in Aruba Instituut voor Tropische Geneeskunde KU Leuven Universiteit Antwerpen
BACKGROUND: Chikungunya virus (CHIKV) emerged in Aruba for the first time in 2014. We studied the clinical presentation of acute CHIKV infection and the contribution of serologic and molecular assays to its diagnosis. In a cohort of confirmed CHIKV cases, we analysed the frequency, duration and predictors of post-chikungunya chronic polyarthralgia (pCHIK-CPA), defined as joint pains lasting longer than 6 weeks or longer than 1 year.
...