Publicaties
Gekozen filters:
Gekozen filters:
Targeted delivery of adamantylated peptidoglycan immunomodulators in lipid nanocarriers : NMR shows that cargo fragments are available on the surface Universiteit Gent
Identification of the molecular determinants involved in antimicrobial activity of pseudodesmin A, a cyclic lipopeptide from the viscosin group Universiteit Gent
Cyclic lipo(depsi)peptides (CLiPs) from Pseudomonas constitute a class of natural products involved in a broad range of biological functions for their producers. They also display interesting antimicrobial potential including activity against Gram-positive bacteria. Literature has indicated that these compounds can induce membrane permeabilization, possibly through pore-formation, leading to the general view that the cellular membrane ...
Adamantane containing peptidoglycan fragments enhance RANTES and IL-6 production in lipopolysaccharide-induced macrophages Universiteit Gent
Synthesis and conformational properties of 3,4-difluoro-L-prolines Universiteit Gent
Molecular model for the self-assembly of the cyclic lipodepsipeptide pseudodesmin A Universiteit Gent
Five-membered ring pucker conformational analysis of novel fluorinated prolines Universiteit Gent
Fluorination of amino acids has become a relevant tool in protein engineering as a way to induce property changes such as enhanced stability, foldability and hydrophobicity while only introducing a small steric cost.1,2 Furthermore, it also enables the use of 19F NMR which, due to the sensitivity of the 19F nucleus and the low natural abundance of fluorine in biological molecules, can provide well-resolved and site-specific information.3 ...
Quantification of the electrostatic and covalent interaction between whey proteins and low methoxyl pectin using PFG-NMR diffusometry Universiteit Gent
Fluorescent Pseudomonas and cyclic lipopeptide diversity in the rhizosphere of cocoyam (Xanthosoma sagittifolium) Universiteit Gent
Conformation and dynamics of the cyclic lipopeptide viscosinamide at the water-lipid interface Universiteit Gent
Cyclic lipodepsipeptides or CLiPs from Pseudomonas are secondary metabolites that mediate a wide range of biological functions for their producers, and display antimicrobial and anticancer activities. Direct interaction of CLiPs with the cellular membranes is presumed to be essential in causing these. To understand the processes involved at the molecular level, knowledge of the conformation and dynamics of CLiPs at the water-lipid interface is ...