TLR3 controls constitutive IFN-beta antiviral immunity in human fibroblasts and cortical neurons KU Leuven
Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency KU Leuven
The new IVD Regulation 2017/746: a case study at a large university hospital laboratory in Belgium demonstrates the need for clarification on the degrees of freedom laboratories have to use lab-developed tests to improve patient care KU Leuven
NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation KU Leuven
Infectious diseases epidemiology, quantitative methodology, and clinical research in the midst of the COVID-19 pandemic: Perspective from a European country KU Leuven
ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation Vrije Universiteit Brussel
BACKGROUND: Bone destruction is a hallmark of multiple myeloma (MM). It has been reported that proteasome inhibitors (PIs) can reduce bone resorption and increase bone formation in MM patients, but the underlying mechanisms remain unclear.
METHODS: Mesenchymal stem cells (MSCs) were treated with various doses of PIs, and the effects of bortezomib or carfilzomib on endoplasmic reticulum (ER) stress signaling pathways were analyzed by ...