Retrotransposon biomarkers

The invention relates to methods of tumor analysis relying on the detection of expression of or of changes in the expression levels of specific retrotransposons. Such methods find application in, amongst other, predicting the response of a tumor to immunotherapy or to immunogenic therapy, and in following up such responses. The expression levels of specific retrotransposons can thus be used in determining which patients are most likely to respond to immunotherapy or immunogenic therapy. Corresponding diagnostic kits are likewise part of the invention.

Octrooi-publicatienummer: WO2020165361

Jaar aanvraag: 2020

Jaar toekenning: 2021

Jaar van publicatie: 2020

Status: Aangevraagd

Technologiedomeinen: Biotechnologie

Gevalideerd voor IOF-sleutel: Ja

Toegewezen aan: Associatie KULeuven