Onderzoeker
Bram Laukens
- Disciplines:Biofysica, Moleculaire en celbiologie, Medische biochemie en metabolisme, Laboratoriumgeneeskunde, Microbiologie, Systeembiologie, Plantenbiologie, Medicinale en biomoleculaire chemie, Biochemie en metabolisme
Affiliaties
- Vakgroep Biomedische Moleculaire Biologie (Departement)
Lid
Vanaf1 okt 2009 → 30 jun 2015 - Vakgroep Biochemie en Microbiologie (Departement)
Lid
Vanaf22 sep 2009 → 31 dec 2017
Projecten
1 - 1 of 1
- Glyco-engineering van IL-10 en IL-22 voor weefselspecifieke aflevering via lectine-receptorenVanaf1 okt 2009 → 26 feb 2015Financiering: IWT persoonsgebonden financ. - specialisatiebeurzen
Publicaties
1 - 10 van 14
- GlycoVHH : optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery(2023)
Auteurs: Loes van Schie, Wander Van Breedam, Charlotte Roels, Martin Frank, Ahmadreza Mehdipour, Bram Laukens, Wim Nerinckx, Francis Santens, Simon Devos, Iebe Rossey, et al.
- Knockout of RSN1, TVP18 or CSC1-2 causes perturbation of Golgi cisternae in Pichia pastoris(2021)
Auteurs: Rochelle Aw, Charlot De Wachter, Bram Laukens, Michiel De Bruyne, David Bell, Karen M. Polizzi
Pagina's: 48 - 63 - Yeast-secreted, dried and food-admixed monomeric IgA prevents gastrointestinal infection in a piglet model(2019)
Auteurs: Vikram Virdi, Jorge Palací Bataller, Bram Laukens, Stefan Ryckaert, Eric Cox, Erik Vanderbeke
Pagina's: 527 - 530 - Optimized expression of the Starmerella bombicola lactone esterase in Pichia pastoris through temperature adaptation, codon-optimization and co-expression with HAC1(2018)
Auteurs: Stijn De Waele, Isabel Vandenberghe, Bram Laukens, Sören Planckaert, Stijn Verweire, Bart Devreese, Katarzyna Ciesielska
Pagina's: 62 - 70 - A simple colorimetric assay for measuring fructosamine 3 kinase activity(2017)
Auteurs: Justin C Cikomola, Antoine S Kishabongo, Karl Vandepoele, MARIEKE DE MULDER, Philippe B Katchunga, Bram Laukens, Loes van Schie, Hendrik Grootaert, Marijn Speeckaert
Pagina's: 154 - 163 - N-glycosylation engineering in Pichia pastoris for protein therapeutics: advancing the GlycoSwitch and introducing GlycoDelete(2016)
Auteurs: Bram Laukens
- Modular integrated secretory system engineering in Pichia pastoris to enhance G-protein coupled receptor expression(2016)
Auteurs: Katrien Claes, Kristof Vandewalle, Bram Laukens, Toon Laeremans, Olivier Vosters, Ingrid Langer, Marc Parmentier, Jan Steyaert
Pagina's: 1070 - 1075 - A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris(2016)
Auteurs: Fabrice Cerini, Hubert Gaertner, Knut Madden, Ilya Tolstorukov, Scott Brown, Bram Laukens, Jay C Harner, Anna M Oommen, John T Harms, Anthony R Sump, et al.
Pagina's: 1 - 10 - Engineering yeast for producing human glycoproteins : where are we now?(2015)
Auteurs: Bram Laukens, Charlotte De Visscher
Pagina's: 21 - 34 - Engineering the Pichia pastoris N-glycosylation pathway using the GlycoSwitch technology(2015)Series: Methods in Molecular Biology
Auteurs: Bram Laukens, Charlot De Wachter, Alexandra Castilho
Pagina's: 103 - 122
Patenten
1 - 7 van 7
- Means and methods for generating complex glycans derived from fungal engineered hosts (Inventor)
- Glycosylation of variable immunoglobulin domains (Inventor)
- MEANS AND METHODS FOR ORAL PROTEIN DELIVERY (Inventor)
- Means and methods for generating complex glycans derived from fungal engineered hosts (Inventor)
- Glycosylation of variable immunoglobulin domains (Inventor)
- MEANS AND METHODS FOR ORAL PROTEIN DELIVERY (Inventor)
- Means and methods for generating complex glycans derived from fungal engineered hosts (Inventor)