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Organisatie
Annaert Lab
Research Group
Hoofdorganisatie:VIB-KU Leuven Center for Brain & Disease Research
Tijdsduur:1 jan 2017 → Heden
Organisatieprofiel:Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
Trefwoorden:Neurobiology, neurodevelopment, neurodegeneration, Alzheimer, Parkinson, ALS
Disciplines:Bio-informatica en computationele biologie, Moleculaire en celbiologie, Neurowetenschappen
Huidige onderzoekers
1 - 9 of 9 results
- Annaert Wim (Verantwoordelijke)
- Charlotte Collier (Lid)
- Thomas Leroy (Lid)
- Katherine North (Lid)
- Ivan Ramos Calvo (Lid)
- Ragna Sannerud (Lid)
- Zoë Van Acker (Lid)
- Céline Vrancx (Lid)
- Xiaojuan Yang (Lid)
Projecten
1 - 10 of 11
- Presenilin2 in endolysosomal homeostasis: a focus on membrane contact sitesVanaf1 aug 2023 → HedenFinanciering: Andere int. instellingen niet elders genoemd
- Unraveling the role of presenilin1 in organellar calcium homeostasisVanaf1 jan 2023 → HedenFinanciering: Andere int. instellingen niet elders genoemd
- A role for Presenilin 2/?-secretase in endolysosomal homeostasis of human neurons and microglia: relevance to Alzheimer’s diseaseVanaf1 jan 2023 → HedenFinanciering: Privé-financiering van binnenlandse oorsprong - onbepaald
- VIB Grant for Annaert Lab_Period:2022-01-01-2026-12-31Vanaf1 jan 2022 → HedenFinanciering: VOI - Projectmatig onderzoek
- On the role of Presenilins in interorganellar communication and Ca2 + handlingVanaf1 jan 2021 → 31 dec 2023Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
- The lysosomal exonuclease PLD3 as a late-onset Alzheimer risk factorVanaf1 jun 2020 → 31 mei 2023Financiering: Andere int. instellingen niet elders genoemd
- An integrated in vitro and in vivo study to unravel the function of VPS13C, the first genetic risk factor in Lewy Body diseaseVanaf1 jan 2019 → 31 dec 2020Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
- New neuronal models for intracellular toxic Aß accumulationVanaf1 jun 2018 → 31 mei 2021Financiering: Andere int. instellingen niet elders genoemd
- Role of ARF6 in PSEN1 mediated endo-lysosomal defectsVanaf1 jan 2018 → 31 dec 2019Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
- Regulation of Presenilin2-mediated intracellular ab accumulation and effects and lysosomalVanaf1 jan 2017 → 31 dec 2018Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
Publicaties
1 - 10 van 33
- Endo-lysosomal dysregulations and late-onset Alzheimer's disease: impact of genetic risk factors.(2019)
Auteurs: Zoë Van Acker, Marine Bretou, Willem Annaert
Pagina's: 20 - Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson's disease.(2021)
Auteurs: Stefanie Smolders, David Crosiers, Anne Sieben, Elisabeth Hens, Sara Van Mossevelde, Roberto Alexandre Dos Santos Dias, Willem Annaert, Christine Van Broeckhoven
Pagina's: 25 - Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export.(2019)
Auteurs: Willem Annaert
Pagina's: 3521 - Characterization of Influenza Virus Pseudotyped with Ebolavirus Glycoprotein(2018)
Auteurs: Willem Annaert
Pagina's: e00941-17 - Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism.(2023)
Auteurs: Zoë Van Acker, Anika Perdok, Katherine North, Ragna Sannerud, Marine Bretou, Willem Annaert
Pagina's: 2847 - Structural Determinant of ß-Amyloid Formation: From Transmembrane Protein Dimerization to ß-Amyloid Aggregates.(2022)
Auteurs: Céline Vrancx
Pagina's: 2753 - ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.(2021)
Auteurs: Ragna Sannerud, Rupert Mayer, Patrizia Agostinis, Willem Annaert, Francis Impens
Pagina's: 100182 - The role of Bcl-2 proteins in modulating neuronal Ca2+ signaling in health and in Alzheimer's disease.(2021)
Auteurs: Willem Annaert
Pagina's: 118997 - Superparamagnetic Nanoparticles for Lysosome Isolation to Identify Spatial Alterations in Lysosomal Protein and Lipid Composition.(2020)
Auteurs: Willem Annaert
Pagina's: 100122 - Epithelial-to-mesenchymal-like transition events in melanoma.(2022)
Auteurs: Dennis Pedri, Panagiotis Karras, Ewout Landeloos, Jean-Christophe Marine, Florian Rambow
Pagina's: 1352-1368