Clinical Implementation of NIPT - Technical and Biological Challenges

Non-invasive prenatal testing (NIPT) for fetal aneuploidy detection is increasingly being offered in the clinical setting. Whereas the majority of tests only report fetal trisomies 21, 18 and 13, genome wide analyses have the potential to detect other fetal, as well as maternal, aneuploidies. In this review we discuss the technical and clinical advantages and challenges associated with genome wide cell free fetal DNA profiling.

Jaar van publicatie:2016

BOF-keylabel:ja

IOF-keylabel:ja

BOF-publication weight:1

CSS-citation score:2

Authors from:Higher Education

Toegankelijkheid:Closed