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Integrating optical waveguides in electrowetting-on-dielectric digital microfluidic chips

Tijdschriftbijdrage - Tijdschriftartikel

Readout through a microscope-based setup is one of the most prevalent optical detection methods used in current digital (i.e. droplet-based) electrowetting-on-dielectric lab-on-chip devices. The integration of waveguides on such devices allows further size and complexity reduction for absorption, fluorescence and surface plasmon resonance based detection mechanisms. In this paper, we show a straightforward method to integrate multimode polymer optical waveguides on an EWOD device. A proof-of-concept system is presented that allows droplets to be transported by EWOD actuation to a gap between two opposing waveguides down to 300 μm in size, and engulf the integrated waveguides for transmission measurements. The system is validated using a gold nanoparticle based model assay. © 2013 Elsevier B.V.
Tijdschrift: Sensors and Actuators B, Chemical
ISSN: 0925-4005
Volume: 181
Pagina's: 166 - 171
Jaar van publicatie:2013
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:6
CSS-citation score:1
Authors from:Higher Education
Toegankelijkheid:Open