Projects
Development of an alternative testing strategy for the fish early life-stage test for predicting chronic toxicity. University of Antwerp
Identification, characterization and validation of modifiers of repeat RNA toxicity in C9orf72 amyotrophic lateral sclerosis (ALS) KU Leuven
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the degeneration of upper and lower motor neurons in the motor cortex, brainstem and spinal cord. With an average survival of 3-5 years and a lack of effective therapies, there is a high unmet medical need for new therapeutic interventions. The most frequent genetic cause of both familial (40%) and sporadic ALS (4%) is caused by a non-coding repeat ...
Market-oriented validation of SAFETY96: Method for determining a toxicity and/or growth promotion effect of a treatment or compound Hasselt University
FORX - FOod interventions to Reduce immunotherapy toXicity Vrije Universiteit Brussel
Promotor: Sandrine Aspeslagh
Effects of the chemical structure of per- and polyfluoroalkyl substances (PFAS) on the bioaccumulation and toxicity to terrestrial and aquatic plants and invertebrates. University of Antwerp
Investigating fatty acid toxicity in amyotrophic lateral sclerosis KU Leuven
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease of the adult motor system. In 2040, the number of ALS patients will increase by 69%, making it urgent to develop new treatments. ALS is characterized by the loss of upper and lower motor neurons, leading to progressive paralysis and, inevitably, death within 3 to 5 years of diagnosis. Hyperexcitability is a common pathologic feature and is associated with a worse ...