Researcher
Dries Knapen
- Research interest:Aquatic toxicology, zebrafish, adverse outcome pathways, stress physiology, systems biology, developmental biology, embryonic development, alternative testing approaches
- Keywords:ECOTOXICOLOGY, FISH ECOTOXICOLOGY, TOXICOLOGY, REPRODUCTIVE PHYSIOLOGY AND TOXICITY, ENVIRONMENTAL TOXICOLOGY, EMBRYOTOXICITY, Biology
- Disciplines:Environmental impact and risk assessment
- Research techniques:Zebrafish embryo test, zebrafish test, alternative in chemico and in vitro tests
- Users of research expertise:Toxicology, ecotoxicology
Affiliations
- Veterinary physiology and biochemistry (Research group)
Member
From1 Oct 2010 → Today - Systemic Physiological and Ecotoxicological Research (SPHERE) (Research group)
Member
From1 Oct 2003 → 30 Sep 2010
Projects
1 - 10 of 36
- Partnership for the Assessment of Risks from Chemicals (PARC).From1 May 2022 → TodayFunding: Horizon Europe - Health
- Thyroid hormone system disruption during early and late zebrafish embryo development.From1 Oct 2021 → TodayFunding: BOF - doctoral mandates
- Vital crop growth through usage of microalgaebased biostimulants (VIGOROUS).From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Elucidating the pathogenicity of genetic variants of uncertain significance in Brugada syndrome patients by functional modelling in hiPSC-derived cardiomyocytes and zebrafishFrom1 Nov 2020 → TodayFunding: FWO fellowships
- Development of a guidance document for improving zebrafish welfare in laboratory animal facilities.From1 Sep 2020 → TodayFunding: Department of Environment
- SPHERE LAB: An accredited body for ecotoxicological risk assessment.From1 Sep 2020 → 31 Aug 2021Funding: IOF - technology validation in real environment
- From exposome to effect assessment of contaminants in human and animal models (EXPOSOME).From1 Jan 2020 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - research organisations
- An integrated multi-purpose basic infrastructure for dynamic and sensitive metabolic profiling of cells and embryos.From1 Jan 2020 → 31 Dec 2021Funding: BOF - scientific equipment program
- Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation (ERGO).From1 Jan 2019 → TodayFunding: H2020 - Health, demographic change and wellbeing
- The role of the paraoxonase gene family in obesity and obesity-associated liver disease following exposure to environmental pollutants or medical intervention strategies.From1 Jan 2019 → TodayFunding: BOF - projects
Publications
1 - 10 of 86
- Sublethal effect concentrations for nonpolar narcosis in the zebrafish embryo(2021)
Authors: Riccardo Massei, Dries Knapen, Adrian Covaci, Ronny Blust, Philipp Mayer, Lucia Vergauwen
Pages: 2802 - 2812 - Evidenced-based approaches to support the development of endocrine-mediated adverse outcome pathways(2021)
Authors: Karine Audouze, Elias Zgheib, Khaled Abass, Asma H. Baig, Isabel Forner-Piquer, Henrik Holbech, Dries Knapen, Pim E.G. Leonards, Diana I. Lupu, Saranya Palaniswamy, et al.
Number of pages: 10 - ERGO(2020)
Authors: Henrik Holbech, Peter Matthiessen, Martin Hansen, Gerrit Schüürmann, Dries Knapen, Marieke Reuver, Frédéric Flamant, Laurent Sachs, Werner Kloas, Klara Hilscherova, et al.
Pages: 1 - 18 - Toward an AOP network-based tiered testing strategy for the assessment of thyroid hormone disruption(2020)
Authors: Dries Knapen, Evelyn Stinckens, Jenna E. Cavallin, Gerald T. Ankley, Henrik Holbech, Daniel L. Villeneuve, Lucia Vergauwen
Pages: 8491 - 8499 - An adverse outcome pathway-based tiered testing strategy for the assessment of thyroid hormone disruption in fish(2020)Edition: 99Volume: 99
Authors: Evelyn Stinckens, Dries Knapen, Hilda Witters, Lucia Vergauwen
Number of pages: 2 - Effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish(2020)
Authors: Evelyn Stinckens, Lucia Vergauwen, Brett R. Blackwell, Gerald T. Ankley, Daniel L. Villeneuve, Dries Knapen
Pages: 6213 - 6223 - Thyroid hormone disruptors interfere with molecular pathways of eye development and function in zebrafish(2019)
Authors: Lisa Baumann, Helmut Segner, Albert Ros, Dries Knapen, Lucia Vergauwen
Number of pages: 17 - The use of zebrafish feeding trials for the safety assessment of genetically modified crops(2019)Edition: 99Volume: 99
Authors: Isabelle Gabriëls, Dries Knapen, Marc De Loose, Lucia Vergauwen
Number of pages: 221 - Advancing the Zebrafish embryo test for endocrine disruptor screening using micro-injection(2019)
Authors: Ellen Michiels, Lucia Vergauwen, Foon Yin Lai, Raewyn Town, Adrian Covaci, Alexander van Nuijs, Steven Van Cruchten, Dries Knapen
Pages: 533 - 547 - Chemical hazard prediction and hypothesis testing using quantitative adverse outcome pathways(2019)
Authors: Edward J. Perkins, Kaylan Gayen, Jason E. Shoemaker, Philipp Antczak, Lyle Burgoon, Francesco Falciani, Steve Gutsell, Geoff Hodges, Aude Kienzler, Dries Knapen, et al.
Pages: 91 - 102