Riboproteogenomics of the sORF-encoded Salmonella peptidome Ghent University
Recent developments in the field of ribosome profiling enabled the measurement of translation on a genome-wide scale by massive parallel sequencing of ribosome-protected messenger RNA fragments When combined with trapping of initiating 70S ribosomes at start codons, the genome-wide identification of small open reading frames (sORFs) and de novo translation start site assignment in bacteria is facilitated Viewing their greatly understudied ...