Projects
First-Principles Study of the Mechanical Properties of Ultra-Thin Films and Complex Gate Stacks KU Leuven
The recent technological progresses in lithography and patterning techniques used in the integration of nanoelectronic devices open the possibility to create complex multilayer stacks and devices, strongly scaled down and whose nanometer scale properties have an unknown impact on the electrical and mechanical performances. Therefore, being able to capture the mechanical properties of nanoscaled layers is of fundamental importance to not only ...
Model-based characterization of the mechanical niche of mouse fetal liver hematopoietic stem cells. KU Leuven
Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) would theoretically provide an inexhaustible pool of HSCs, suitable for transplantation or for the generation of blood cells for transfusion. Although immature HSCs can be generated from PSCs, they do not robustly engraft and cannot yet be used to generate large numbers of hematopoietic cells.
The behavior of somatic stem cells is regulated by their ...
QuantumLignin: Elucidating the interactions of lignin building blocks with their environment for the creation of additive models by means of quantum mechanical modelling. Hasselt University
Assessment of Mechanical Dyssynchrony as Selection Criterion for CRT Treatment KU Leuven
Cardiac resynchronization therapy (CRT) is a frequently used treatment for patients with heart failure and conduction disorders, in which the contraction of the left ventricle is resynchronized using a special pacemaker with multiple electrodes. However, current clinical guideline criteria for patient selection result in approximately 35% of patients not responding to therapy. Some studies suggest that such non-responders may even be at ...
Manufacturing and mechanical characterization of vitrimer composites Ghent University
Existing composite-manufacturing technologies will be utilised to produce quality glass- and/or carbon- Fibre Reinforced Vitrimer Composites (FRVCs). Epoxy-based vitrimers will be used as matrices reinforced with continuous and/or short fibres. State-of-the-art methodologies will be applied to perform in-depth characterization of FRVCs; mechanical characterisation, temperature dependent behaviour, evaluation of re-processability ...
The differential geometry of nonholonomic mechanical systems University of Antwerp
Understanding role of mechanical forces in human neural tube development and neural tube defects KU Leuven
The formation of the neural tube is the earliest event in the establishment of the central nervous system. Cell acquire their identity at the same time as the tissue undergoes large-scale tissue deformations, driven by cellular contractility and mechanical forces. However, the relationship between these tissue deformations, the developed mechanical forces and the establishment of cellular identities remains largely unexplored. In addition, it ...
Mechanical and rheological characterization of micro-tissues for tissue engineering KU Leuven
This PhD is focused on advancing bone tissue engineering by investigating chondrogenic organoids, which closely mimic the natural bone development process and have shown promise in enhancing tissue engineering outcomes. The project encompasses three main objectives: First, the characterization of mechanical and rheological properties of chondrogenic organoids and tissue spheroids using atomic force microscopy. Second, the measurement of ...
Mechanical analyzer for recycled and sustainable fibers and filaments Ghent University
A unique device that determines the performance of individual fibers and filaments. With this, we are capitalizing on the urgent industrial need to develop more sustainable new and recycled materials. Short-term valorization through integration into accredited synthetic turf service lab, middle-to-long term valorization for recycled and sustainable materials in broader textiles and composite industry.