Projects
Receptor tyrosine kinase signaling in heart failure with preserved ejection fraction University of Antwerp
Therapeutic potential of high-density lipoproteins in heart failure with reduced ejection fraction KU Leuven
Plasma high-density lipoprotein (HDL) cholesterol levels and plasma levels of its major apolipoprotein (apo), apo A-I, are inversely correlated with the incidence of coronary heart disease. The potential protection conferred by HDL against ischemic cardiovascular diseases has been most often attributed to its role in reverse cholesterol transport. However, HDLs exert divergent functions that include actions mediated by signalling via ...
Matricellular proteins, Thrombospondin-2 en SPARC (Osteonectine) protect against heart failure. KU Leuven
Coordination and authorship of the guideline chronic heart failure University of Antwerp
The effect of extended heart failure Audit and Feedback on cardiovascular hospitalizations in general practice: a randomized controlled trial KU Leuven
Identification of small molecule ErbB4 agonists for treatment of heart failure. University of Antwerp
Metabolomic and cellular modifications induced by cardiac resynchronization therapy in heart failure patients. Hasselt University
MiCrovasculaR rarefaction in vascUlar Cognitive Impairement and heArt faiLure KU Leuven
Vascular dementia and heart failure represent major health burden to morbidity, mortality and quality of life. Comorbidities (hypertension, aging, diabetes, etc.) affect all organs, but the brain and heart are especially sensitive to these chronic stresses resulting in cognitive impairment (a mental disorder) and heart failure (a non-mental disorder). These comorbidities also induce a reduction in microvascular density, called microvascular ...
Active microvascular regression drives diastolic dysfunction leading to heart failure KU Leuven
Heart disease is the most important cause of mortality in westernized nations, with heart failure, which is when the heart cannot pump sufficient blood, being the most prominent cause of hospitalizations in Europe. More than half of the heart failure patients have heart failure with preserved ejection fraction (HFpEF). HFpEF occurs in patients that present with additional disorders such as diabetes and hypertension. There is currently no ...