Projects
Foundations of expressive timing control in music Ghent University
Timing is a crucial aspect of meaningful musical communication. In order to achieve the intended musical expression, musicians need to control their movements such that time-critical musical structures can be adequately performed. In the past, foundations of timing have been based on cognitive theory. However, we believe that an embodied approach may offer new insights that are of fundamental importance to music research. In particular, we ...
Expressive moments in augmented music realities Ghent University
The goal of the project is to study expressive moments in augmented music realities. Expressive
moments are subjective experiences of optimal interaction with, or guided by, music, such as flow,
euphoria, and ecstasy. These moments will be studied in settings that involve collective musicmaking
in augmented music environments. The environments include technologies to measure
physical and ...
Productivity, constructionalization and "expressive" constructions: Tracking productivity shifts in Belgian and Netherlandic 19th to 21st Century Dutch Ghent University
The project focuses on shifts in the constructional productivity of two clusters of "expressive" constructions in Belgian and Netherlandic Dutch since 1800, viz. (i) binominal patterns of the een schat van een kind-type and (ii) intensifying-resultative constructions such as Hij werkte zich dood, with a view to shedding more light on the relation between increasing productivity and constructionalization.
Differential expression and secretion of microRNAs by specific cardiac fibroblast phenotypes KU Leuven
The heart is composed of many cells types, out of which cardiac myocytes and fibroblasts form the majority. Cardiac myocytes are the muscle cells, which are responsible for the rhythmic beating of the heart. Fibroblasts produce proteins which maintain the architecture of the heart. However, after heart attack whereby muscle cells are lost (infarction), fibroblasts modify themselves to become myofibroblasts. These cells produce collagen that ...
Molecular imaging of HER2 expression of breast carcinoma with radiolabeled Nanobodies Vrije Universiteit Brussel
High-resolution differential expression analysis for single-cell RNA-seq data Ghent University
Single-cell RNA-sequencing (scRNA-seq) is a novel technology that measures transcript expression (i.e., messenger RNA abundance) at the level of single cells.
While some biological systems consist of clearly separated groups (cell types), others are characterized by a smooth transition in cellular states, often represented as trajectories, e.g. the development of stem cells to mature cells. Based on the identified cell types or ...
Methods for differential expression analysis in single-cell transcriptomics at the gene- and transcript-level Ghent University
The field of single-cell transcriptomics (scRNA-seq) is currently experiencing a massive boom in popularity. It enables researchers to study gene expression in individual cells, revolutionizing their view on complex biological processes as development and disease. The technology is extremely high-throughput; it measures the expression of thousands of genes in up to 10000 cells per sample, giving scientists a bird's-eye view on the gene ...
Metabolism without GLUT4, UCP1 and leptin: mRNA expression analysis in chicken. KU Leuven
When analysing gene expression of >20 tissues in mice, we discovered the phenomenon of “disallowed” genes (financially supported by FWO - G067212N). Last year, we started analysis of evolutionary conservation of “disallowed genes” by defining a core set of mRNA encoding genes that are commonly present in the genomes of humans, chickens, lizards and coelacanth, representing 4 major classes of vertebrate life. Taking human genes as reference ...
Hide your Pain: Pain expression and pain sensitivity in the face of social threat KU Leuven
Pain is usually studied on an intrapersonal level, ignoring the social context in which it occurs. However, humans are social beings and concerning painful experiences the social environment has important effects on our behavior and experience. Research has shown that social factors have a profound influence on pain perception. For instance, when we are socially excluded, it hurts in a similar way as physical pain would. To date, very little ...