Researcher
Katrien Remaut
- Keywords:lipid nanoparticles, mRNA delivery, innate immunity, peritoneal carcinomatosis, non-viral gene delivery, ocular gene therapy
- Disciplines:Nanobiotechnology, Other biological sciences not elsewhere classified, Environmental safety and health of nanotechnology, Nanoscale characterisation, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, Biopharmaceuticals, In vitro testing, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2001 → Today
Projects
1 - 10 of 20
- Let There Be Light: two biophotonic approaches to boost retinal ganglion cell transplantation as a cure for blindnessFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Genetic therapy for EYS- and USH2A-associated retinal dystrophy ("GET-READY")From1 Jun 2021 → TodayFunding: FWO research project
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2020 → 31 Oct 2021Funding: BOF - doctoral mandates
- Precision medicine in inherited blindness using integrated omics in human and animal modelsFrom1 Jan 2020 → TodayFunding: BOF - projects
- Barriers and carriers for non-viral delivery of mRNA to induce transient protein expression in the retina: the hurdles of the inner limiting membrane and innate immunity versus the potential of mRNA self-amplification.From1 Nov 2019 → TodayFunding: FWO fellowships
- Barriers and carriers for non-viral delivery of mRNA to induce transient protein expression in the retina: the hurdles of the inner limiting membrane and innate immunity versus the potential of mRNA self-amplification.From1 Oct 2019 → 1 Nov 2019Funding: BOF - doctoral mandates
- Intraperitoneal nebulization of thermosensitive hydrogels for the controlled release of chemotherapeutics and biopharmaceuticals to treat peritoneal carcinomatosisFrom1 Jan 2019 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- High pressure intraperitoneal aerosolization of chemotherapeutics, nanoparticles and hydrogels to treat peritoneal carcinomatosis: effect on tumor penetration, biodistribution and anti-cancer activity.From1 Jan 2019 → TodayFunding: FWO research project
Publications
1 - 10 of 80
- Laser-induced nanobubbles safely ablate vitreous opacities in vivo(2022)
Authors: Félix Sauvage, Van Phuc Nguyen, Yanxiu Li, Aranit Harizaj, J. Sebag, Dimitri Roels, Viktor Van Havere, Karen Peynshaert, Ranhua Xiong, Juan Carlos Fraire, et al.
Pages: 552 - 559 - Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy(2022)
Authors: An-Katrien Minnaert, Loes van Schie, Hendrik Grootaert, Jonas Himpe, Simon Devos, Wannes Weyts, Herlinde De Keersmaecker, Kevin Braeckmans, Elisabeth Van Aken, Joris Delanghe, et al.
- Together is better : mRNA coU+2010encapsulation in lipoplexes is required to obtain ratiometric coU+2010delivery and protein expression on the single cell level(2021)
Authors: Heyang Zhang, Jeroen Bussmann, Florian H. Huhnke, Joke Devoldere, An-Katrien Minnaert, Wim Jiskoot, Friedhelm Serwane, Joachim Spatz, Magnus Röding, Stefaan De Smedt, et al.
- Aerosolization of thermosensitive hydrogels using pressurized intraperitoneal aerosol chemotherapy (PIPAC)(2021)Volume: 28
Authors: Mohammad Rahimi Gorji, Helena Braet, Charlotte Debbaut, Ghader Ghorbaniasl, Sarah Cosyns, Wouter Willaert, Katrien Remaut, Wim Ceelen
Pages: S110 - S110 - Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across(2021)
Authors: An-Katrien Minnaert, Helena Vanluchene, Rein Verbeke, Sabine Lentacker, Stefaan De Smedt, Koen Raemdonck, Niek Sanders, Katrien Remaut
- Lipoplexes to deliver oligonucleotides in gram-positive and gram-negative bacteria : towards treatment of blood infections(2021)
Authors: Sara Pereira, Rita Sobral Santos, Luís Moreira, Nuno Guimarães, Mariana Gomes, Heyang Zhang, Katrien Remaut, Kevin Braeckmans, Stefaan De Smedt, Nuno Filipe Azevedo
- Exploring high pressure nebulization of pluronic F127 hydrogels for intraperitoneal drug delivery(2021)
Authors: Helena Braet, Mohammad Rahimi Gorji, Charlotte Debbaut, G Ghorbaniasl, Thibault Van Walleghem, Senne Cornelis, Sarah Cosyns, Chris Vervaet, Wouter Willaert, Wim Ceelen, et al.
Pages: 134 - 143 - Vaccinia virus protein B18R : influence on mRNA immunogenicity and translation upon non-viral delivery in different ocular cell types(2021)
Authors: An-Katrien Minnaert, Joke Devoldere, Karen Peynshaert, Laure Vercruysse, Stefaan De Smedt, Katrien Remaut
- Control over the fibrillization yield by varying the oligomeric nucleation propensities of self-assembling peptides(2020)
Authors: Chun Yin Jerry Lau, Federico Fontana, Laurens D. B. Mandemaker, Dennie Wezendonk, Benjamin Vermeer, Alexandre M. J. J. Bonvin, Renko de Vries, Heyang Zhang, Katrien Remaut, Joep van den Dikkenberg, et al.
- Hyaluronic acid coating of gold nanoparticles for intraocular drug delivery : evaluation of the surface properties and effect on their distribution(2020)
Authors: P. S. Apaolaza, M. Busch, E. Asin-Prieto, Karen Peynshaert, R. Rathod, Katrien Remaut, N. Dünker, A. Göpferich