Development of a cluster in the area of high-tech medical systems as a spearhead in the further development of the Eindhoven-Leuven-Aachen triangle (ELAt). KU Leuven
Study of the essential function of beta-actin in embryonic development and the necessity for correct localisation of beta-actin MRNA during neuronal development Ghent University
Through analysis of the B-actin knock-out en knock-in mice, and derived cell lines thereof, we will study the essential functions of B-actin in development (more specific in vascularisation and neuronal differentiation) and the role of the 3'UTR in correct localization and function of B-actin. Several methods will be used, including in situ immunostaining, primary cell cultures, RNAi and differential proteome analysis.
Regulation of placental development in horses: reciprocal parental control of angiogenesis in equine placenta and abnormal placental development. Ghent University
Pathological conditions of the placenta have significant effects on the health of fetus and mother. In mares, pathological conditions, such as fetal growth retardation, placentitis and hydrops, are associated with compromised placental vascularization. Using high-throughput data, we aim to gain insight into the regulatory mechanisms of vascularization in the normal and abnormal placenta and provide fundamental information on placental ...
Study of the essential function of beta-actin in embryonic development and the necessity of correct localisation of beta-actin mRNA in neuronal development Ghent University
The actin cytoskeleton is the driving force for various cell motility processes. Little is known about the function of the six actin isoforms during mammalian development. During this PhD, we will investigate how loss of beta-actine influences angiogenesis and neurogenesis during embryogenesis and how mislocalisation of beta-actine mRNA leads to aberrant neuronal differentiation and angiogenesis.
Experimental evolution in Candida biofilms: does drug tolerance facilitate drug resistance development in fungi?Experimental evolution in Candida biofilms: does drug tolerance facilitate drug resistance development in fungi? KU Leuven
Antifungal resistance is emerging on a scale that has never been documented before. Invasive, multidrug-resistant fungal infections are posing an increasing threat to public health, further complicated by the availability of only three major antifungal drug classes. The antifungal resistance crisis is embodied by the novel ‘superbug’ C. auris. After its first identification in 2009, this opportunistic pathogen has emerged worldwide and shown ...
Approaching patterns of social and sustainable regional development. An interdisciplinary dialogue between past and present on the region of Sagalassos. KU Leuven
Teachers’ pedagogical content knowledge (PCK) (Shulman, 1986b) is an important predictor of educational quality and student outcomes (e.g., Baumert et al., 2010; Kunter et al., 2013). Hence, it is an important task of teacher education to contribute to PCK development in the best possible way. The present project aims at a better understanding of the development of PCK. The project focuses on primary (pre-service) teachers’ PCK of French as a ...
Approaching patterns of nature-society interactions in regional development. An interdisciplinary dialogue between past and present in the region of Sagalassos. KU Leuven
The project wishes to initiate an innovative dialogue between archaeology, ecology, geography and planning studies in the region of Sagalassos (SW Turkey). The purpose is to investigate diachronic co-evolution of society and nature and tie the Sagalassos Archaeological Research Project to a parcours of sustainable regional development.
In regards to the past, the applicants wish to contribute to debates in social and regional ...