Projects
Clinical and genetic epidemiology of Parkinson's disease: focus on disease progression and non-motor symptoms. University of Antwerp
Clinical and genetic epidemiology of Parkinson's disease: focus on disease progression and non-motor symptoms. University of Antwerp
Clinical, electrophysiological and molecular genetic characterization of HMSN type II and intermediate type of CMT. University of Antwerp
High throughput molecular diagnostics in individual patients for genetic diseases with heterogeneous clinical presentation (TECHGENE). KU Leuven
The human genetic and immunological determinants of the clinical manifestations of SARS-CoV-2 infection: Towards personalised medicine KU Leuven
The consequences of SARS-CoV-2 exposure range from a lack of infection to lethal COVID-19. This immense inter-individual clinical variability is the key scientific and medical enigma in the field. While age and certain co-morbidities are known to influence disease outcome, these parameters do not explain all variation. In addition, there are other SARS-CoV-2 phenotypes of clinical importance: multisystem inflammatory syndrome in children and ...
Clinical, immunological and genetic unravelling of severe isolated central nervous system disorders in children. KU Leuven
Neuroimmune disorders in previously healthy children often have a
detrimental outcome. Unfortunately, an integrated view on the
pathophysiology and genetic causes, combining neurological and
immunological insight, is lacking. However increased knowledge of
the molecular pathogenesis could significantly improve the
management of these diseases. Several inborn errors of immunity
(IEI) underlie ...
EPISTOP: Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic model of epilepsy – tuberous sclerosis complex Vrije Universiteit Brussel
...
Genetic origin of congenital heart defects in Tunisian population ( a clinical and laboratory approach) KU Leuven
Congenital heart defects (CHD) are the most common type of birth defect and account for nearly one-third of all major congenital anomalies. In Tunisia, CHD represent a major cause of infant morbidity and mortality. Their incidence is estimated to be 6.8 per 1000. The general objective of this study is to determine the genetic causes of congenital heart defects in Tunisian patients. This knowledge and expertise thus gained will contribute to a ...