Projects
Immunoassay design of a fiber optic biosensor for medical and agro-food applications KU Leuven
Over the last decades, biosensors have emerged as innovative tools at the interface between advanced biotechnology and sensor technology. They have been used in multiple applications, ranging from agricultural industry and food safety to medical diagnosis and environmental monitoring, and they have drawn increasing commercial attention from the market. The ever increasing cost in the healthcare sector has driven the research towards ...
INNOVATIVE NUCLEIC ACID BASED STRATEGIES FOR FIBER OPTIC SURFACE PLASMON RESONANCE BIOSENSOR DESIGN KU Leuven
The diverse information embedded in the specific sequence of DNA molecules has been feeding our understanding and insights in disease heritage, spreading and evolution. Ultrasensitive detection of the DNA molecules themselves is crucial for the early-stage detection of several diseases, as it facilitates the minimization of actual disease burden. Gold standard technologies, such as the polymerase chain reaction (PCR), are mainly restricted to ...
Designing affinity-based nanoswitches on a fiber optic surface plasmon resonance biosensor for continuous biomarker monitoring. KU Leuven
The development of an in vivo system for the site-specific modification of proteins with 'click' functionalized amino acids for biosensor applications Hasselt University
PROJECT SERENE: Novel bioSEnsor for REal-time in vivo NEurotransmitter monitoring KU Leuven
ThermoSens: Moving thermal biosensor platforms from principles to applications KU Leuven
Photochromic biosensors and imaging for interaction sensing at low expression levels KU Leuven
The complex processes that take place within the biological cell often involve interactions between multiple molecules, and occur within a specific spatio-temporal context. Fluorescence imaging has become a solid standard for visualizing such processes within the native environment. By using fluorescent labeling strategies, it couples the cellular distribution and activity of biomolecules to a fluorescence-based signal and microscopic ...
Development of genetically encoded biosensors for super-resolution optical fluctuation imaging KU Leuven
Life is dynamic, defined by the ability to maintain homeostasis in ever-changing environments. On a cellular level, this requires an intricate regulatory network to manage activities and reactivities in response to external stimuli. Fluorescence microscopy provides us a window into this dynamic realm of subcellular signalling. The complex spatiotemporal regulation of this network can be investigated with fluorescent indicators, remarkable ...
Super resolution fluorescence microscopy of biomolecular interactions with photochromic biosensors and complementation. KU Leuven
Fluorescence microscopy techniques are indispensable research tools that have enabled live cell imaging with low invasiveness, high sensitivity, and high spatiotemporal resolution. As a result, fluorescence microscopy has revolutionized our understanding of the inner workings of single cells and whole organisms. An integral part of the imaging performance is the fluorescent labels, as the quality of the labels influences the quality of the ...