Projects
SAILor: Safe Artificial Intelligence and Learning for Verification. University of Antwerp
The use of artificial intelligence for EEG-based diagnosis of epilepsy after a first seizure Ghent University
Epilepsy is the fourth most common neurological disorder and affects around 50 million people worldwide. Today diagnosis is based on clinical history, EEG measurements and MRI imaging. However, 50-99% of the MRIs and up to 70% of the EEGs may give negative results, despite an underlying epileptic disorder. Differential diagnosis of epilepsy is further complicated by isolated seizures and other disorders that may give rise to seizure-like ...
Zirconium(IV)/Cerium(IV) bimetallic metal organic frameworks as novel redox active artificial proteases: a systematic study of molecular interactions and catalytic properties KU Leuven
Metal Organic Frameworks (MOFs) are a fascinating new class of porous material with applications ranging from gas storage for hydrogen power, absorptive materials for kidney dialysis, to novel catalysts for protein cleavage (hydrolysis). They are formed of metaloxygen clusters joined by carbon-based linkers to form highly structured crystals with well-defined pores. By varying the metal and linker species, an infinite range of MOFs can be ...
Towards Bottom-up Artificial Cell Design with Precision Macromolecules Ghent University
Transient processes continuously proceed in cells: molecule signaling is amplified and diminishes after a certain amount of time, which activates or deactivates cell function including cell division or programmed cell death. During cell division, proteins form stiff, tube-like structures called microtubules to anchor chromosomes and drag them to their envisaged new position. The microtubule’s assemby is a transient process as well and ...
Is artificial intelligence a game changer for diversity at work? A sociomaterial study of the effects of algorithmic HR analytics on HRM practice and equal opportunities Hasselt University
An integrated study on the effects of long term exposure to artificial light at night in free-living great tits (Parus major) and on the effectiveness of mitigating strategies. University of Antwerp
Parallel optimization of complex industrial yeast traits using a highly evolvable artificial neochromosome KU Leuven
The budding yeast Saccharomyces cerevisiae is a powerful model organism in eukaryotic cell biology. Moreover, it is also one of the most frequently used microbes in today’s biotechnology. Interestingly, during its long association with human activity, it gradually adapted to man-made fermentation environments. However, new biotech applications, such as biofuel production, confront them with new, harsh environments to which it is not yet fully ...
Zirconium(IV) containing organic frameworks as a novel class of artificial proteases: Selective hydrolysis and molecular interaction studies KU Leuven
Selective hydrolytic cleavage of the peptide bond in proteins is one of the most important procedures in analytical biochemistry and biotechnology applications. However, this is a challenging task due to the extreme inertness of peptide bond. Commonly used natural proteases are expensive and operate only in a narrow temperature and pH range. They often suffer from self-digestion and often have limited selectivity. Therefore, new, efficient, ...
Zirconium(IV) Containing Organic Frameworks as a Novel Class of Artificial Proteases: Catalytic and Molecular Interaction Studies KU Leuven
Selective hydrolytic cleavage of the peptide bond in proteins is one of the most important procedures in analytical biochemistry and biotechnology applications. However, this is a challenging task due to the extreme inertness of peptide bond. Commonly used natural proteases are expensive and operate only in a narrow temperature and pH range. They often suffer from self-digestion and often have limited selectivity. Therefore, new, efficient, ...