Functional properties of sensory nerves and neuro-endocrine cells in airway hyper-reactivity KU Leuven
Rhinitis is a common disease characterized by mucosal irritation, excessive nasal secretions and congestion, leading to reduced life quality and substantial economic burden. Previously, we showed that in animal models and in rhinitis patients the sensory innervation hyper-reacts to noxious chemicals stimulating Transient Receptor Potential (TRP) cation channels. Furthermore, we found in clinical trials that targeting the sensory innervation ...