Projects
A search for better insights and new targets in the prevention and reversal of obesity and type 2 diabetes. KU Leuven
Prevention of heart failure in type 2 diabetes by exercise intervention Ghent University
Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...
Prevention of heart failure in type 2 diabetes by exercise intervention KU Leuven
Cardiac dysfunction is highly prevalent in type 2 diabetes (T2DM), leading to adverse cardiac events and premature death. In the last few years the global longitudinal strain (GLS, which can be assessed during echocardiography) was found to predict this diabetes-induced heart failure (DIHF) years ahead in T2DM patients. We have now recently shown that GLS indeed is disturbed even in well-controlled and symptom-free T2DM patients: a disturbed ...
Prevention of heart failure in type 2 diabetes by exercise intervention Hasselt University
Interplay between the skeleton and glucose homeostasis in the context of type 2 diabetes mellitus KU Leuven
Metabolic disorders such as osteoporosis, obesity and diabetes represent a global health concern, affecting millions of people worldwide. These conditions are linked in many ways. Type 2 diabetes mellitus (T2DM) impacts negatively on glucose homeostasis and multiple organs, including the skeleton, typically leading to poor bone quality, increased fracture risk, and impaired bone regeneration. Conversely, bone itself also affects energy ...
Breaking the Chain: Addressing the Syndemic of type 2 diabetes, depression, and socio-economic vulnerability. University of Antwerp
A search for new pathways in the reversal and prevention of obesity and type 2 diabetes KU Leuven
Obesity is a chronic disease that mainly develops in sedentary individuals, over-consuming a Western diet, rich in salt, sugar and fat. Obesity is a major cause of several life threatening health risks, such as type 2 diabetes (T2D). The currently available drugs have rather disappointing long-term effects. Gastric bypass procedures (GBP) have turned out to be a very effective treatment for obesity and associated T2D with a maintained effect ...
Run, daddy, run! A multicomponent mHealth lifestyle intervention for the prevention of overweight, obesity and type 2 diabetes: engaging fathers and their children. Ghent University
Overweight, obesity and type 2 diabetes (T2D) are currently the most serious and challenging health problems. Engaging in sufficient levels of physical activity (PA) and limiting sitting(sedentary) behaviour (SB) can help in reducing the prevalence of overweight, obesity and T2D. Evidence has shown that family-based lifestyle interventions are effective in improving health behaviours of both children and parents. However, it is often seen ...
Relation between residual beta cell function and glycemic variability in (pre) type 1 diabetes Ghent University
Type 1 diabetes develops when 60 to 90% of insulin-producing beta cellsahve been destroyed. This cell loss leads to greater variability of
blood glucose levels both before and after diagnosis. This variability is predictive of progression to clinical onset of diabetes in risk groups and of
frequenc of hypoglycemic events in patients. Novel beta cell therapy trials aim to prevent or cure diabetes by trying to preserve or restore ...