Projects
Anti-kanker therapie versterkt door kleine radioactief gelabelde compounds met affiniteit voor necrosis (sRALNAC): een Prrof-of-Principle experiment ter ondersteuning van een nieuw patent aanvraag. KU Leuven
Oncogenese en resistentie tegen therapie bij bloedkankers begrijpen en gerichten Ghent University
Acute leukemia, both of myeloid and lymphoid origin, is a very prevalent cancer in kids and adults. Unfortunately, frontline radiation and chemotherapy causes lasting cognitive problems and can also lead to secondary cancers. Additionally, about one-fourth of children and 50% of adults with acute leukemia develop resistance to therapy or relapse post therapy.
Mechanisms of resistance are poorly understood and current research on ...
CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease (OZR EU Bonus). Vrije Universiteit Brussel
Designing cell-type specific enhancers for CNS Gene Therapies. University of Antwerp
Advanced cell models and multifunctional nanomaterials for light-mediated cancer therapies KU Leuven
Discovery of novel therapies for patients with CF not eligible for registered modulator treatments, assisted by novel microfluidic techniques for combinatorial, high-throughput organoid screens KU Leuven
INNOVATIVE THERAPIES FOR LINE-1 DISEASE KU Leuven
Back to the future: virus-host interactions guide the development of future gene therapies. KU Leuven
We aim to enhance our understanding of virus-host interactions in the context of AAV replication and apply this knowledge to develop more efficient gene therapy vectors and to increase the efficacy of vector production. Equally, we have drawn inspiration from natural AAV isolates for the engineering of AAV vectors that may be better suited for targeting human tissues than currently available AAV vectors, and have applied these vectors to ...