Study of the earliest lesions in Crohn's disease in the post-operative recurrence model. KU Leuven
Crohns disease (CD) is a chronic inflammatory bowel disease, with (bloody) diarrhea and abdominal pain as major symptoms. The pathogenesis of CD is still unknown, but its thought that the chronic intestinal inflammation in CD results from an inappropriate and ongoing activation of the mucosal immune system against the normal luminal microbiota in genetically susceptible persons, most likely facilitated by defects in both the intestinal ...