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Researcher
Paul Rutgeerts
- Disciplines:Endocrinology and metabolic diseases, Gastro-enterology and hepatology, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 1999 → 30 Sep 2015
Projects
1 - 10 of 10
- Identification of the role of matrix metalloproteinases (MMP's) in the development and persistence of chronic bowel inflammation.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project
- Influence of microbiota on intestinal stem cell behavior, differentiation and migration in patients with inflammatory bowel disease.From1 Oct 2010 → 30 Sep 2013Funding: FWO fellowships
- Study of the earliest lesions in Crohn's disease in the post-operative recurrence model.From1 Oct 2010 → 31 Oct 2015Funding: FWO fellowships
- Can inhibitors of the fibrinolytic system be used either as a marker or as a target to decrease the prothrombotic state observed in IBD patients.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
- Study of the interaction between the gut flora and the mucosal immune system in the earliest lesions of Crohn's disease in the postoperative recurrence model.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- The study of genetic, immunologic and microbiologic factors in the etiopathogenesis of Crohns disease and ulcerative colitis.From1 Oct 2009 → 31 Dec 2011Funding: BOF - Concerted Research Project from 1994
- Impact of the mucosal detoxification mechanism of hydrogen sulphide on the butyrate metabolism in ulcerative colitis.From1 Jan 2009 → 31 Dec 2012Funding: FWO research project (including WEAVE projects)
- Identification of (new) susceptibility genes for Crohn's disease and their functional meaning.From1 Oct 2008 → 31 Jul 2015Funding: FWO fellowships
- The role of the innate immune system and of autophagy in the genetic susceptibility and disease-expression of inflammatory bowel diseases.From1 Oct 2008 → 1 Aug 2010Funding: FWO fellowships
- Genome-wide copy number variation association analysis to identify the genetic determinants in Crohn's disease.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
Publications
1 - 10 of 474
- Correlation of Stool Frequency and Abdominal Pain Measures With Simple Endoscopic Score for Crohn's Disease(2020)
Authors: Paul Rutgeerts
Pages: 304 - 313 - IM-UNITI: Three-year Efficacy, Safety, and Immunogenicity of Ustekinumab Treatment of Crohn's Disease(2020)
Authors: Paul Rutgeerts
Pages: 23 - 32 - Early Dose Optimisation of Golimumab in Nonresponders to Induction Treatment for Ulcerative Colitis Is Effective and Supported by Pharmacokinetic Data(2019)
Authors: Paul Rutgeerts
Pages: 1257 - 1264 - Immunogenicity of Golimumab and its Clinical Relevance in Patients With Ulcerative Colitis(2019)
Authors: Paul Rutgeerts
Pages: 1532 - 1540 - Combination Therapy With Infliximab and Azathioprine Improves Infliximab Pharmacokinetic Features and Efficacy: A Post Hoc Analysis(2019)
Authors: Paul Rutgeerts
Pages: 1525 - + - Efficacy and Safety of Adalimumab by Disease Duration: Analysis of Pooled Data From Crohn's Disease Studies(2019)
Authors: Paul Rutgeerts
Pages: 725 - 734 - Difference in Pathomechanism Between Crohn's Disease and Ulcerative Colitis Revealed by Colon Transcriptome(2019)
Authors: Ingrid Arijs, Paul Rutgeerts, Séverine Vermeire
Pages: 722 - 731 - Continuous Clinical Response Is Associated With a Change of Disease Course in Patients With Moderate to Severe Ulcerative Colitis Treated With Golimumab(2019)
Authors: Paul Rutgeerts
Pages: 163 - 171 - Gene Expression Signature for Prediction of Golimumab Response in a Phase 2a Open-Label Trial of Patients With Ulcerative Colitis(2018)
Authors: Paul Rutgeerts
Pages: 1008 - + - Efficacy of Ustekinumab for Inducing Endoscopic Healing in Patients With Crohn's Disease(2018)
Authors: Paul Rutgeerts
Pages: 1045 - 1058
Patents
1 - 1 of 1
- MUCOSAL GENE SIGNATURES (Inventor)